Gemnani Rinkle R, Parepalli Avinash, Kumar Sunil, Acharya Sourya, Shukla Samarth
Department of Medicine, Jawaharlal Nehru Medical College, Wardha, IND.
Department of Pathology, Jawaharlal Nehru Medical College, Wardha, IND.
Cureus. 2023 Jun 20;15(6):e40692. doi: 10.7759/cureus.40692. eCollection 2023 Jun.
Non-cirrhotic portal hypertension (NCPH) is a poorly understood condition attributed to various causes in the absence of liver cirrhosis. One of the important and rare conditions leading to NCPH is myeloproliferative neoplasms and blood coagulation abnormalities, which infiltrate the liver cells leading to stasis and raised sinusoidal pressure. We present a rare case of a 40-year-old male who presented to our emergency department with complaints of hematemesis and Malena and was later diagnosed with NCPH associated with chronic myeloid leukemia (CML). This case report emphasizes the importance of considering rare causes of NCPH like CML while evaluating such cases.
非肝硬化性门静脉高压症(NCPH)是一种病因不明的疾病,在无肝硬化的情况下由多种原因引起。导致NCPH的重要且罕见的病症之一是骨髓增殖性肿瘤和血液凝固异常,它们浸润肝细胞导致血流淤滞和肝血窦压力升高。我们报告一例罕见病例,一名40岁男性因呕血和黑便到我院急诊科就诊,后来被诊断为与慢性粒细胞白血病(CML)相关的NCPH。本病例报告强调了在评估此类病例时考虑像CML这样的NCPH罕见病因的重要性。