Ochoa-Diaz Andrés Felipe, Díaz-Jurado Jonathan Javier, Suárez-Ospino Natalia Isabel, Silva-Martínez Paula Andrea, Fajardo-Rivero Javier Enrique
Department of Internal Medicine, Industrial University of Santander, Bucaramanga, Colombia.
University of Santander, Bucaramanga, Colombia.
Thorac Res Pract. 2023 Jul;24(4):228-230. doi: 10.5152/ThoracResPract.2023.22113.
Austrian syndrome corresponds to the triad of meningitis, pneumonia, and endocarditis caused by Streptococcus pneumoniae, there is no global or local incidence given the infrequency of entity. Scarce cases are published in Latin America, with none of them in Colombia. A case of Austrian syndrome by penicillin-resistant S. pneumoniae in an immunocompetent patient is presented. Aortic valve is the most frequent site involved in Austrian syndrome; this patient had an unusual localization of the vegetation on the right coronary artery ostium. The prognosis is poor with a mortality rate of 30% or higher, this patient survived despite systemic complications. Vaccination status impacts in prevention and severity of cases because responsible serotypes are often included in available vaccines. The patient had a serotype covered by available vaccines; however, her vaccination status was unknown. Thus, we present the first case reported in Colombia of Austrian syndrome by a penicillin-resistant S. pneumoniae, in a patient with no identified comorbidities or toxicological history, with a successful evolution.
奥地利综合征表现为肺炎链球菌引起的脑膜炎、肺炎和心内膜炎三联征,鉴于该病症罕见,尚无全球或局部发病率数据。拉丁美洲发表的病例稀少,哥伦比亚尚无相关病例报道。本文报告了一例免疫功能正常患者由耐青霉素肺炎链球菌引起的奥地利综合征病例。主动脉瓣是奥地利综合征最常累及的部位;该患者赘生物位于右冠状动脉开口处,位置异常。预后较差,死亡率达30%或更高,该患者虽出现全身并发症但存活下来。疫苗接种情况对病例的预防和严重程度有影响,因为相关血清型通常包含在现有疫苗中。该患者的血清型在现有疫苗覆盖范围内;然而,其疫苗接种情况未知。因此,我们报告了哥伦比亚首例由耐青霉素肺炎链球菌引起的奥地利综合征病例,患者无明确合并症或毒理学病史,病情进展顺利。