Heart Center Dresden, Department of Cardiac Surgery, Technical University of Dresden, Germany.
Braz J Infect Dis. 2012 Sep-Oct;16(5):486-8. doi: 10.1016/j.bjid.2012.08.003. Epub 2012 Sep 11.
This is the case of a young male suffering from Austrian syndrome, which is the triad of endocarditis, meningitis, and pneumonia due to invasive S. pneumoniae infection. He reported recurrent fever for six months without any antibiotic treatment, which may have determined the further course of the syndrome. Echocardiography revealed massive native valve endocarditis, and the patient was considered for ultima-ratio cardiac surgery. Intraoperative aspect presented extensive affection of the aortic root with full destruction of aortic valve, mitral valve, and aortomitral continuity. The myocardium showed a phlegmon-like infiltration. Microbiologic testing of intraoperatively collected specimens identified penicillin-sensitive Streptococcus pneumoniae. S. pneumoniae is a very uncommon cause for infective infiltrative endocarditis and is associated with severe clinical courses. Austrian syndrome is even more rare, with only a few reported cases worldwide. In those patients, only early diagnosis, immediate antibiotic treatment, and emergent cardiac surgery can save lives.
这是一位患有奥地利综合征的年轻男性患者，该综合征的三联征为侵袭性肺炎链球菌感染引起的心内膜炎、脑膜炎和肺炎。他报告说持续发热六个月，未接受任何抗生素治疗，这可能决定了该综合征的进一步病程。超声心动图显示大量原发性瓣膜心内膜炎，患者被认为需要进行终极心脏手术。术中发现主动脉根部广泛受累，主动脉瓣、二尖瓣和瓣下结构完全破坏。心肌呈脓性浸润。术中采集标本的微生物学检测鉴定出青霉素敏感型肺炎链球菌。肺炎链球菌是感染性浸润性心内膜炎非常罕见的病因，与严重的临床病程相关。奥地利综合征更为罕见，全球仅有少数报道病例。在这些患者中，只有早期诊断、立即抗生素治疗和紧急心脏手术才能挽救生命。
