Zech P, Pozet N
Nouv Presse Med. 1979 Feb 10;8(7):495-8.
A retrospective study made of 114 cases of renovascular hypertension was undertaken to compare the effectiveness of different types of treatment. In this series, with a follow-up of 18 months to 9 years, a favourable result with regard to blood pressure was obtained in 45% of cases with surgery, in 63% of cases with medical treatment and in 88% of cases if treatment included beta-blockers. Medical treatment represents a valid alternative to surgery in hypertension of this type, regardless of the amount of renin secretion and whatever the criteria of ischaemia. The choice of surgery as a method of treatment thus depends above all upon the age of patient, the type of stenosis and the anatomical risk represented by the vascular malformation. Despite the very spectacular results of medical treatment, it remains essential to seek a renal cause for hypertension, since many renal conditions which require specific treatment present with hypertension alone.
对114例肾血管性高血压患者进行了一项回顾性研究,以比较不同治疗方法的效果。在该系列研究中,随访时间为18个月至9年,手术治疗的患者中45%血压得到良好控制,药物治疗的患者中63%血压得到良好控制,若治疗包括β受体阻滞剂则88%的患者血压得到良好控制。对于此类高血压,无论肾素分泌量多少以及缺血标准如何,药物治疗都是手术的有效替代方案。因此,选择手术作为治疗方法首先取决于患者年龄、狭窄类型以及血管畸形所代表的解剖学风险。尽管药物治疗效果显著,但寻找高血压的肾脏病因仍然至关重要,因为许多需要特殊治疗的肾脏疾病仅表现为高血压。