Hurd H, Arme C
Parasitology. 1986 Aug;93 ( Pt 1):111-20. doi: 10.1017/s0031182000049866.
Female Tenebrio molitor infected with metacestodes of Hymenolepis diminuta exhibit elevated concentrations of female-specific proteins in their haemolymph and the origin of these has been investigated. Following a 4 h in vitro incubation with [14C]leucine, fat bodies from non-infected females secreted 13 times more protein than those from females 12 days post-infection. A comparison of the uptake in vivo of radio-isotope labelled amino acids by ovaries from non-infected and infected beetles of various ages revealed no differences; however, a 51.5% decrease in protein sequestration was detected in females 12 days post-infection. Electrophoresis of homogenates of radio-isotope labelled ovaries demonstrated that the majority of label was associated with vitellin sub-units. It is suggested that the decrease in vitellogenin sequestration associated with infection results in an increase in the haemolymph concentration of these proteins despite a concomitant reduction in their secretion by fat bodies. Both fat body synthesis and ovarian sequestration are under juvenile hormone control and it is proposed that metacestodes of H. diminuta may cause a reduction in the concentration of this hormone in the intermediate host.
感染微小膜壳绦虫中绦期幼虫的黄粉虫雌性个体，其血淋巴中雌性特异性蛋白浓度升高，并且对这些蛋白的来源进行了研究。在用[¹⁴C]亮氨酸进行4小时体外孵育后，未感染雌性个体的脂肪体分泌的蛋白比感染后12天的雌性个体的脂肪体多13倍。对不同年龄未感染和感染甲虫的卵巢对放射性同位素标记氨基酸的体内摄取情况进行比较，未发现差异；然而，在感染后12天的雌性个体中，蛋白质螯合减少了51.5%。对放射性同位素标记卵巢匀浆的电泳显示，大部分标记与卵黄蛋白亚基相关。有人认为，与感染相关的卵黄蛋白原螯合减少导致这些蛋白在血淋巴中的浓度升高，尽管脂肪体分泌这些蛋白的量同时减少。脂肪体合成和卵巢螯合均受保幼激素控制，有人提出微小膜壳绦虫的中绦期幼虫可能会导致中间宿主体内该激素浓度降低。
