对广泛耐药宋内志贺菌感染病例的研究，美国。
Case of Extensively Drug-Resistant Shigella sonnei Infection, United States.
出版信息
Emerg Infect Dis. 2023 Aug;29(8):1708-1711. doi: 10.3201/eid2908.230411.
Abstract
We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.
摘要
我们报道了美国德克萨斯州 1 例免疫功能低下患者的广泛耐药（XDR）宋内志贺菌感染。基质辅助激光解吸/电离飞行时间质谱未能鉴定出 XDR 宋内志贺菌，但全基因组测序准确地对该菌株进行了特征描述。针对新兴的 XDR 宋内志贺菌，一线抗菌药物无效。磷霉素、碳青霉烯类和替加环素是潜在的替代品。
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