Bioinformatics and Human Electrophysiology Laboratory, Department of Informatics, Ionian University, Corfu, Greece.
Adv Exp Med Biol. 2023;1424:167-173. doi: 10.1007/978-3-031-31982-2_18.
Alzheimer's disease is a progressive disease that is caused by the destruction of brain neurons. It seems it affects a large group of the world's population that is estimated around 47 million and is expected to triple by 2050. Slowly but surely, the patient's condition is deteriorating, due to the increase of symptom severity, rendering him/her in need of special care. A great percentage of these cases can be attributed to some common modifiable risk factors such as hypertension, obesity, a lack of exercise, alcohol misuse, smoking, unhealthy diet, and a low level of education. The Finnish Geriatric Intervention Study (FINGER Study) proves that some interventions focused on the abovementioned risk factors of the individual's daily life can contribute to delay the occurrence of Alzheimer's disease. Concurrently, the rapid development of smart devices encourages the use of health applications that provide guiding tools and suggestions based on the user's status. The outcome of this paper is the development of a mobile application, to implement and monitor the interventions proposed by the FINGER Study. Based on the user's profile, it offers the ability to evaluate the likelihood of cognitive decline, monitor the process, and help delay the disease's occurrence.
阿尔茨海默病是一种渐进性疾病,由大脑神经元的破坏引起。据估计,它影响了全球约 4700 万人,预计到 2050 年将增加两倍。由于症状严重程度的增加,患者的病情在缓慢但肯定地恶化,导致他们需要特殊护理。这些病例中有很大一部分可以归因于一些常见的可改变的风险因素,如高血压、肥胖、缺乏运动、酗酒、吸烟、不健康的饮食和低教育水平。芬兰老年干预研究(FINGER 研究)证明,一些针对个人日常生活中上述风险因素的干预措施有助于延缓阿尔茨海默病的发生。同时,智能设备的快速发展鼓励使用健康应用程序,这些应用程序根据用户的状态提供指导工具和建议。本文的研究成果是开发了一款移动应用程序,用于实施和监测 FINGER 研究提出的干预措施。根据用户的个人资料,它能够评估认知能力下降的可能性,监测进展,并有助于延缓疾病的发生。