From the Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, BeijingKey Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.
Clin Nucl Med. 2023 Sep 1;48(9):826-827. doi: 10.1097/RLU.0000000000004771. Epub 2023 Jul 22.
Neoplasms that cause tumor-induced osteomalacia are very rarely located in the lung. A 27-year-old man underwent a surgery in the right femoral head to remove the tumor that induced osteomalacia 8 years ago with complete symptomatic relief. However, his bone pain occurred again recently, which lead to suspicion of a recurrent tumor-induced osteomalacia. 68 Ga-DOTATATE PET/CT images showed a pulmonary nodule with mildly increased uptake along with increased activity in the left foot. The pulmonary nodule was subsequently resected and was pathologically confirmed as a phosphaturic mesenchymal tumor. The symptoms were completely relieved postsurgery.
导致肿瘤性骨软化症的肿瘤很少位于肺部。一名 27 岁男性，8 年前因右股骨头肿瘤性骨软化症行手术切除，症状完全缓解。但最近再次出现骨痛，考虑复发性肿瘤性骨软化症。68Ga-DOTATATE PET/CT 图像显示肺部结节伴有轻度摄取增加，同时左足活性增加。随后切除肺部结节，病理证实为磷酸化解偶联肿瘤。术后症状完全缓解。
