UMR MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Montpellier, France.
UMR MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Sète, France; IOC, Indian Ocean Commission, Blue Tower, Rue de l'Institut, Ebène, Mauritius.
Mar Pollut Bull. 2023 Sep;194(Pt B):115267. doi: 10.1016/j.marpolbul.2023.115267. Epub 2023 Jul 22.
Macroplastics are ubiquitous in aquaculture ecosystems. However, to date the potential role of plastics as a support for bacterial biofilm that can include potential human pathogenic bacteria (PHPB) and antibiotic-resistant bacteria (ARB) has been largely overlooked. In this study, we used a combination of metabarcoding and standard antibiotic susceptibility testing to study the pathobiome and resistome of macroplastics, fish guts and the environment in a marine aquaculture farm in Mauritius. Aquaculture macroplastics were found to be higher in PHPB, dominated by the Vibrionaceae family (0.34 % of the total community), compared with environmental samples. Moreover, isolates from aquaculture plastics showed higher significant multiple antibiotic resistance (MAR) compared to non-plastic samples of seawater, sediment and fish guts. These results suggest that plastics act as a reservoir and fomite of PHPB and ARB in aquaculture, potentially threatening the health of farmed fish and human consumers.
养殖生态系统中广泛存在着大型塑料。然而，迄今为止，塑料作为支持细菌生物膜的潜在作用（其中可能包括潜在的人类病原菌和抗生素耐药菌）在很大程度上被忽视了。在这项研究中，我们使用组合代谢组学和标准抗生素药敏试验来研究毛里求斯一家海水养殖场的大型塑料、鱼类肠道和环境中的pathobiome 和 resistome。与环境样本相比，养殖用大型塑料中存在更多的病原菌，主要是弧菌科（占总群落的 0.34%）。此外，与非塑料样本（海水、沉积物和鱼肠）相比，来自养殖塑料的分离株显示出更高的显著多重抗生素耐药性。这些结果表明，塑料在水产养殖中充当病原菌和抗生素耐药菌的储库和媒介，可能对养殖鱼类和人类消费者的健康构成威胁。
