Metropolitan Veterinary Associates, Norristown, Pennsylvania, United States.
The Ohio State University Veterinary Medical Center, Columbus, Ohio, United States.
Vet Comp Orthop Traumatol. 2024 Jan;37(1):8-12. doi: 10.1055/s-0043-1771350. Epub 2023 Jul 24.
The aim of this study was to determine the prevalence of contralateral cranial cruciate ligament rupture (CCLR) in dogs 8 years of age or older, weighing more than or equal to 15 kg at the time of first-side CCLR and to assess associated risks.
It is a cross-sectional retrospective study of 831 client-owned dogs METHODS: Medical records of dogs weighing more than or equal to 15 kgs that were more than or equal to 8 years of age at the time of first CCLR diagnosis were reviewed. Data collected included weight, sex, pre-operative tibial plateau angle, co-morbidities, time between diagnosis of first CCLR and diagnosis of contralateral CCLR. Multivariate logistic regression analysis was used to estimate odds ratio. A median follow-up period of over 112.7 months (25th/75th quartiles 75.4/157.7 months) from first CCLR diagnosis was allotted.
Eight-hundred thirty-one dogs were identified and included. About 19.1% (159/831 dogs, 95% confidence interval: 16.6-22.0%) of dogs that experience a first-side CCLR at 8 years of age or older will rupture the contralateral side, a median of 12.9 months (25th/75th quartiles 6.5/24.3 months) later. Age ( = 0.003) and breed, Golden Retrievers ( = 0.028) and Labrador Retrievers ( = 0.007), were factors significantly associated with contralateral CCLR.
The prevalence of contralateral CCLR in medium-to-large breed dogs more than or equal to 8 years of age old is less than previously reported and the risk decreases as they age. This important information will help guide owners when deciding to pursue surgical stifle stabilization following CCLR in older dogs.
本研究旨在确定 8 岁及以上、初次患十字韧带断裂（CCLR）时体重超过或等于 15kg 的犬中对侧 CCLR 的患病率，并评估相关风险。
这是一项 831 只宠物犬的回顾性交叉研究。
回顾初次 CCLR 诊断时体重超过或等于 15kg、年龄超过或等于 8 岁的犬的病历。收集的数据包括体重、性别、术前胫骨平台角、并存疾病、初次 CCLR 诊断与对侧 CCLR 诊断之间的时间。采用多变量逻辑回归分析估计比值比。从初次 CCLR 诊断开始，平均随访时间超过 112.7 个月（25 分位数/75 分位数为 75.4/157.7 个月）。
共确定并纳入 831 只犬。初次 CCLR 发生在 8 岁及以上的犬中，约有 19.1%（159/831 只犬，95%置信区间：16.6-22.0%）会在 12.9 个月后（25 分位数/75 分位数为 6.5/24.3 个月）对侧破裂。年龄（ = 0.003）和品种，金毛猎犬（ = 0.028）和拉布拉多猎犬（ = 0.007），是与对侧 CCLR 显著相关的因素。
8 岁及以上中大型犬对侧 CCLR 的患病率低于先前报道，且随年龄增长风险降低。这一重要信息将有助于指导主人在为老年犬进行 CCLR 后是否选择进行膝关节稳定手术提供参考。
