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躯干皮肤去神经支配后皮肤温度对冷防御的影响。

Effects of skin temperature on cold defense after cutaneous denervation of the trunk.

作者信息

Heath M E, Jessen C

出版信息

Pflugers Arch. 1986 Aug;407(2):175-7. doi: 10.1007/BF00580672.

DOI:10.1007/BF00580672
PMID:3748778
Abstract

In intact goats the core temperature threshold below which heat production increases with falling core temperature, is inversely related to the temperature of the water bath in which they stand and is therefore assumed to be indicative of the central integration of signals from skin and core temperature receptors. The present study shows that a difference in core temperature thresholds for bath temperatures of 35 degrees C and 40 degrees C persisted after denervation of about two-thirds of the skin of the trunk and limbs. Also, for a given combination of skin and core temperatures, heat production was as great or greater after cutaneous denervation as before. It is concluded that, following denervation of the trunk and upper limbs, intact temperature receptors in the non-denervated skin of the legs and tail, and/or also in tissues between the skin and core, provide important and significant inputs to the temperature regulating system. But these inputs cannot explain fully the thermoregulatory responses observed unless it is assumed that the thermosensitivity of these tissues increased.

摘要

在完整的山羊中,核心温度阈值(低于此阈值时,产热会随着核心温度下降而增加)与它们所站立的水浴温度呈负相关,因此被认为是皮肤和核心温度感受器信号中枢整合的指标。本研究表明,在躯干和四肢约三分之二的皮肤去神经支配后,35摄氏度和40摄氏度水浴温度下的核心温度阈值差异仍然存在。此外,对于给定的皮肤和核心温度组合,皮肤去神经支配后的产热与之前一样多或更多。得出的结论是,在躯干和上肢去神经支配后,腿部和尾部未去神经支配皮肤中的完整温度感受器,和/或皮肤与核心之间组织中的完整温度感受器,会向温度调节系统提供重要且显著的输入。但除非假设这些组织的热敏性增加,否则这些输入无法完全解释所观察到的体温调节反应。

相似文献

1
Effects of skin temperature on cold defense after cutaneous denervation of the trunk.躯干皮肤去神经支配后皮肤温度对冷防御的影响。
Pflugers Arch. 1986 Aug;407(2):175-7. doi: 10.1007/BF00580672.
2
Effects of selective cutaneous denervation on hypothalamic thermosensitivity in rats.选择性皮肤去神经支配对大鼠下丘脑温度敏感性的影响。
Pflugers Arch. 1987 Jan;408(1):73-9. doi: 10.1007/BF00581843.
3
Effect of cutaneous denervation of face and trunk on thermoregulatory responses to cold in rats.面部和躯干皮肤去神经支配对大鼠冷刺激体温调节反应的影响。
J Appl Physiol (1985). 1985 Feb;58(2):376-83. doi: 10.1152/jappl.1985.58.2.376.
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Non-cutaneous peripheral thermosensitivity in the goat (Capra hircus).山羊(Capra hircus)的非皮肤外周热敏性。
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Independent clamps of peripheral and central temperatures and their effects on heat production in the goat.山羊外周和核心温度的独立钳夹及其对产热的影响。
J Physiol. 1981 Feb;311:11-22. doi: 10.1113/jphysiol.1981.sp013570.
6
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Pflugers Arch. 1988 Sep;412(4):402-8. doi: 10.1007/BF01907559.
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[Relation between the temperature of different skin layers and changes in the firing of cold cutaneous thermoreceptors].[不同皮肤层温度与冷觉皮肤温度感受器放电变化之间的关系]
Fiziol Zh SSSR Im I M Sechenova. 1980 Dec;66(12):1785-91.
8
[Localization of cold thermoreceptors in various layers of the skin].
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[Firing rate of cold cutaneous thermoreceptors and the intensity of thermoregulatory response development].[冷皮肤温度感受器的放电频率与体温调节反应发展的强度]
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本文引用的文献

1
Independent clamps of peripheral and central temperatures and their effects on heat production in the goat.山羊外周和核心温度的独立钳夹及其对产热的影响。
J Physiol. 1981 Feb;311:11-22. doi: 10.1113/jphysiol.1981.sp013570.
2
Temperature sensitivity of skeletal muscle in the conscious goat.清醒山羊骨骼肌的温度敏感性
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A comparison between total body thermosensitivity and local thermosensitivity in mammals and birds.哺乳动物和鸟类全身热敏感性与局部热敏感性的比较。
Pflugers Arch. 1984 Mar;400(3):228-34. doi: 10.1007/BF00581552.
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The establishment of thermal equilibrium in sheep exposed to cold environments.
Res Vet Sci. 1966 Oct;7(4):454-65.
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Differential thermal sensitivity in the human skin.人类皮肤的差异热敏感性。
Pflugers Arch. 1973;340(1):71-6. doi: 10.1007/BF00592198.
6
Thermal afferents in the control of body temperature.
Pharmacol Ther. 1985;28(1):107-34. doi: 10.1016/0163-7258(85)90085-3.
7
Different types of slowly conducting afferent units in cat skeletal muscle and tendon.猫骨骼肌和肌腱中不同类型的慢传导传入单位。
J Physiol. 1985 Jun;363:403-17. doi: 10.1113/jphysiol.1985.sp015718.
8
Effects of selective cutaneous denervation on hypothalamic thermosensitivity in rats.选择性皮肤去神经支配对大鼠下丘脑温度敏感性的影响。
Pflugers Arch. 1987 Jan;408(1):73-9. doi: 10.1007/BF00581843.
9
Skin and core temperatures as determinants of heat production and heat loss in the goat.皮肤温度和核心温度作为山羊产热和散热的决定因素。
Pflugers Arch. 1986 Jun;406(6):600-7. doi: 10.1007/BF00584027.
10
Effect of cutaneous denervation of face and trunk on thermoregulatory responses to cold in rats.面部和躯干皮肤去神经支配对大鼠冷刺激体温调节反应的影响。
J Appl Physiol (1985). 1985 Feb;58(2):376-83. doi: 10.1152/jappl.1985.58.2.376.