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羧甲基淀粉/黄原胶组合 Pickering 乳液的制备及其对紫檀芪的保护和缓释。

Fabrication of carboxymethyl starch/xanthan gum combinations Pickering emulsion for protection and sustained release of pterostilbene.

机构信息

College of Biology and Food Engineering, Hefei Normal University, Hefei 230601, China.

Anhui Engineering Laboratory for Agro-products Processing, Anhui Agricultural University, Hefei 230036, China.

出版信息

Int J Biol Macromol. 2023 Sep 1;248:125963. doi: 10.1016/j.ijbiomac.2023.125963. Epub 2023 Jul 22.

DOI:10.1016/j.ijbiomac.2023.125963
PMID:37487995
Abstract

Carboxymethyl starch (CMS)/xanthan gum (XG) combinations with different ratios (CMS/XG: 1/1, 3/1, 5/1, 7/1, 9/1, w/w) were used as Pickering emulsion delivery systems to encapsulate pterostilbene (PTS) to improve its stability. The results showed that the Pickering emulsion prepared using CMS/XG combinations could effectively encapsulate PTS. When the mass ratio of CMS to XG was 1:1, the encapsulation efficiency reached 91.20 %. The spherical particles in the PTS emulsion were dissociated and homogenous. The results of backscattered light experiments and storage stability studies showed that the PTS emulsion system prepared using CMS/XG was uniform and stable, with no obvious phase separation or emulsion droplet coalescence. With an increase in the mass ratio of XG, the water distribution in the emulsion became more evenly distributed, and the aggregation of droplets was reduced. The PTS emulsion prepared using CMS/XG improved the storage retention percentage of PTS. The cumulative release of PTS in the simulated gastric fluid was significantly lower than that in simulated intestinal fluid. The Pickering emulsion prepared using CMS/XG combinations can be used as a delivery system for functional foods and help to develop an efficient and reliable release system for hydrophobic bioactive substances.

摘要

羧甲基淀粉(CMS)/黄原胶(XG)以不同比例(CMS/XG:1/1、3/1、5/1、7/1、9/1,w/w)组合作为 Pickering 乳液输送系统,用于封装紫檀芪(PTS)以提高其稳定性。结果表明,使用 CMS/XG 组合制备的 Pickering 乳液可以有效封装 PTS。当 CMS 与 XG 的质量比为 1:1 时,包封效率达到 91.20%。PTS 乳液中的球形颗粒解离且均匀。背散射光实验和储存稳定性研究结果表明,使用 CMS/XG 制备的 PTS 乳液体系均匀稳定,没有明显的相分离或乳液液滴聚结。随着 XG 质量比的增加,乳液中的水分分布更加均匀,液滴的聚集减少。使用 CMS/XG 制备的 PTS 乳液提高了 PTS 的储存保持率。在模拟胃液中的 PTS 累积释放明显低于在模拟肠液中的释放。CMS/XG 组合制备的 Pickering 乳液可用作功能性食品的输送系统,并有助于开发用于疏水性生物活性物质的高效可靠的释放系统。

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