Medical College of Yangzhou University, Yangzhou, People's Republic of China.
Department of General Surgery, General Surgery Institute of Yangzhou, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 98 Nantong West Road, Yangzhou, Jiangsu, 225001, People's Republic of China.
J Gastrointest Surg. 2023 Oct;27(10):2226-2244. doi: 10.1007/s11605-023-05782-x. Epub 2023 Jul 24.
A long-lasting and efficient method of managing obesity and therapeutic associated comorbidities is bariatric surgery. However, a debated comparison between one-anastomosis gastric bypass (OAGB) and sleeve gastrectomy is still essential (SG). The goal of this study is to evaluate outcomes using RCT and NRCT from 2015 to 2022.
By contrasting the OAGB and SG for bariatric surgery from January 2015 to September 2022, an RCT and NRCT were prospectively gathered using the PubMed, Cochrane Library, and MEDLINE databases of published research. This meta-statistical analysis was carried out in RevMan 5.4, and the best effect model was selected based on heterogeneity.
Twelve retrospective studies describing 6344 patients (3725 OAGB and 2619 SG) satisfied the inclusion criteria. A statistically significant result was in %EWL first year (MD = 8.03, 95% CI: 4.54-11.52, P < 0.05), second year (MD = 8.94, 95% CI: 2.95-14.94, P < 0.05), third year (MD = 8.93, 95% CI: 5.75-12.10, P < 0.05), fourth year (MD = 15.09, 95% CI:0.87-29.31, P < 0.05), and fifth year (MD = 14.25, 95% CI: 5.34, P < 0.05). OAGB was associated with a lower rate of remission in dyslipidemia, hypertension, diabetes mellitus, and hemorrhage. However, OAGB increased the incidence of GERD and leakage.
In terms of weight loss and comorbidity remission, OAGB is more effective than SG, although postoperative consequences are rather comparable between the two methods.
减重手术是治疗肥胖症及其相关合并症的一种长期且有效的方法。然而，一种有争议的观点认为，胃旁路手术（OAGB）和袖状胃切除术（SG）之间仍需要进行比较。本研究的目的是评估 2015 年至 2022 年期间随机对照试验（RCT）和非随机对照试验（NRCT）的结果。
通过对比 2015 年 1 月至 2022 年 9 月间用于减重手术的 OAGB 和 SG，我们前瞻性地从 PubMed、Cochrane 图书馆和 MEDLINE 数据库中收集了 RCT 和 NRCT 研究。使用 RevMan 5.4 进行了这项荟萃分析，并根据异质性选择了最佳效应模型。
12 项回顾性研究描述了 6344 名患者（3725 名 OAGB 和 2619 名 SG）符合纳入标准。在第一年（MD=8.03，95%CI：4.54-11.52，P<0.05）、第二年（MD=8.94，95%CI：2.95-14.94，P<0.05）、第三年（MD=8.93，95%CI：5.75-12.10，P<0.05）、第四年（MD=15.09，95%CI：0.87-29.31，P<0.05）和第五年（MD=14.25，95%CI：5.34，P<0.05），OAGB 在 %EWL 方面的效果更显著。OAGB 在缓解血脂异常、高血压、糖尿病和出血方面的效果较差，但 OAGB 增加了胃食管反流病（GERD）和漏诊的发生率。
在体重减轻和合并症缓解方面，OAGB 比 SG 更有效，尽管两种方法的术后后果相当。
