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LSG 与 MGB-OAGB:两种术式 5 年随访数据及长期结果的对比——一项随机对照试验的长期结果

LSG vs MGB-OAGB: 5-Year Follow-up Data and Comparative Outcome of the Two Procedures over Long Term-Results of a Randomised Control Trial.

机构信息

Department of Minimal Access & Bariatric Surgery, Synergy Plus Hospital, NH2, Near Guru Ka Taal, Agra, Uttar Pradesh, 282007, India.

Department of Minimal Access & Bariatric Surgery ILS Hospitals, DD-6, Sector 1, Salt Lake City, Kolkata, West Bengal, 700064, India.

出版信息

Obes Surg. 2021 Mar;31(3):1223-1232. doi: 10.1007/s11695-020-05119-6. Epub 2020 Nov 16.

Abstract

BACKGROUND

Bariatric surgery is a durable and effective way for the management of obesity and resolution of related comorbidities. The aim of this study is to evaluate the outcome of laparoscopic sleeve gastrectomy (LSG) and one-anastomosis gastric bypass (OAGB) over long term in a South Asian population.

MATERIALS AND METHODS

This is a prospective randomised trial comparing the outcome of 100 and 101 LSG and OAGB patients respectively after 5-year follow-up. This study is in continuity with previous published papers with 1- and 3-year follow-up. 71 LSG and 73 OAGB patients followed at 5 years. The results of these patients were analysed and compared in terms of %EWL, comorbidity resolution and quality of life (QoL) at 5 years. Bariatric analysis reporting and outcome system (BAROS) was used to assess the outcome of patients.

RESULTS

At 5-year follow-up, both LSG and OAGB patients performed well and patients had significant improvement in BMI (kg/m. The mean preoperative BMI of LSG and OAGB patients was 44.89 ± 7.94 and 45.32 ± 8.24, and their mean BMI at 5 years was 33.41 ± 6.02, 30.80 ± 3.40 respectively. At 5 years, %EWL was 55.95 ± 27.01 and 65.28 ± 13.98 for LSG and OAGB patients respectively. The QoL score of LSG and OAGB patients was 1.86 ± 0.56 and 2.35 ± 0.41 while comorbidity score was 1.84 ± 0.68 and 2.24 ± 0.62 respectively at 5 years.

CONCLUSIONS

Both LSG and OAGB are effective bariatric procedures over long term with respect to weight loss, comorbidity resolution and improvement in QoL. OAGB is significantly better than LSG in all the three parameters at 5 years.

摘要

背景

减重手术是肥胖症及其相关合并症管理的一种持久且有效的方法。本研究旨在评估腹腔镜袖状胃切除术(LSG)和单吻合口胃旁路术(OAGB)在南亚人群中的长期效果。

材料与方法

这是一项前瞻性随机试验,比较了 100 例 LSG 和 101 例 OAGB 患者分别在 5 年随访后的结果。本研究与之前发表的 1 年和 3 年随访的论文连续进行。5 年时随访了 71 例 LSG 和 73 例 OAGB 患者。分析比较了这些患者的体重减轻百分比(%EWL)、合并症缓解情况和 5 年时的生活质量(QoL)。采用减重分析报告和结果系统(BAROS)评估患者的结果。

结果

在 5 年随访时,LSG 和 OAGB 患者均表现良好,患者 BMI(kg/m²)显著改善。LSG 和 OAGB 患者术前 BMI 的平均值分别为 44.89±7.94 和 45.32±8.24,5 年后 BMI 的平均值分别为 33.41±6.02 和 30.80±3.40。5 年时,LSG 和 OAGB 患者的%EWL 分别为 55.95±27.01 和 65.28±13.98。LSG 和 OAGB 患者的 QoL 评分分别为 1.86±0.56 和 2.35±0.41,合并症评分分别为 1.84±0.68 和 2.24±0.62。

结论

LSG 和 OAGB 都是有效的长期减重手术,在减轻体重、缓解合并症和提高生活质量方面都有效果。OAGB 在 5 年时在所有三个参数上均明显优于 LSG。

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