Juhlin L, Malmros-Enander I
Photodermatol. 1986 Jun;3(3):164-8.
A patient with solar urticaria induced by wavelengths 290-420 nm is reported. Wheals appeared after a few seconds of exposure to the sun; longer exposure caused general malaise and syncope. Intradermal injection of in vitro irradiated plasma caused a local whealing which was not seen with plasma kept dark. The wheals induced by irradiation could be inhibited by local injection of an antihistamine. Local injection of lidocaine and hydrocortisone was ineffective. Depletion of substance P in the skin by topical application of capsaicin did not change the sensitivity to irradiation with 313 nm and a single PUVA treatment did not change the minimal urticarial dose (MUD). Sunscreens were in practice of limited value with the exception of a protective plastic helmet. Repeated daily irradiation with UVA in increasing doses normalized his response to sunlight.
报告了一名由波长290 - 420纳米诱发日光性荨麻疹的患者。暴露于阳光下几秒钟后出现风团；暴露时间延长会导致全身不适和晕厥。皮内注射体外照射的血浆会引起局部风团，而黑暗保存的血浆则不会出现这种情况。照射诱发的风团可通过局部注射抗组胺药来抑制。局部注射利多卡因和氢化可的松无效。局部应用辣椒素使皮肤中的P物质耗竭，并未改变对313纳米照射的敏感性，单次PUVA治疗也未改变最小荨麻疹剂量（MUD）。除了防护塑料头盔外，防晒霜实际上价值有限。每天重复递增剂量的UVA照射使他对阳光的反应恢复正常。
