Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
BMC Res Notes. 2023 Jul 24;16(1):154. doi: 10.1186/s13104-023-06429-5.
Diabetes is the most common metabolic disorder that leads to various complications, and among these complications, disruption in the lipid profile and serum uric acid (SUA) is one of the significant cases that can lead to the deterioration of the health status of patients with diabetes. So, we aimed to evaluate the level of SUA and lipid profiles in patients with diabetes. A total of 230 patients with diabetes who were admitted to Razi Hospital, Rasht, Iran, were enrolled in this study. Demographical data and clinical characteristics of the patients include gender, body mass index (BMI), duration of diabetes, history of smoking, FBS, HbA1c, SUA, Creatinine (Cr), Cholesterol (Chol), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), retinopathy, hypertension, ischemic heart disease (IHD), and microalbuminuria were recorded. All data were analyzed using the SPSS version 21 by a significant level < 0.05.
According to our results, 70 were male, and 160 were female, with a mean age of 57.36 ± 8.05 years and a mean BMI of 28.10 ± 4.62. The most frequent comorbidities were hypertension, 67%. The serum level of FBS, HBA1c, SUA, Cr, Chol, LDL, HDL, and TG were 191.47 ± 71.66 mg/dL, 7.94 ± 1.21 mg/dL, 5.65 ± 1.95 mg/dL, 0.94 ± 0.16 mg/dL, 167.28 ± 45.22 mg/dL, 95.91 ± 37.03 mg/dL, 39.78 ± 10.44 mg/dL, and 186.75 ± 76.65 mg/dL, respectively. Only UA had a significant relationship with TG level (P < 0.05).
糖尿病是最常见的代谢紊乱疾病，可导致多种并发症，其中血脂谱和血清尿酸（SUA）的紊乱是导致糖尿病患者健康状况恶化的重要原因之一。因此，我们旨在评估糖尿病患者的 SUA 和血脂谱水平。本研究共纳入 230 名在伊朗拉什特拉齐医院就诊的糖尿病患者。患者的人口统计学数据和临床特征包括性别、体重指数（BMI）、糖尿病病程、吸烟史、空腹血糖（FBS）、糖化血红蛋白（HbA1c）、SUA、肌酐（Cr）、胆固醇（Chol）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、甘油三酯（TG）、视网膜病变、高血压、缺血性心脏病（IHD）和微量白蛋白尿。所有数据均采用 SPSS 版本 21 进行分析，显著性水平 < 0.05。
根据我们的结果，70 名患者为男性，160 名患者为女性，平均年龄为 57.36 ± 8.05 岁，平均 BMI 为 28.10 ± 4.62。最常见的合并症是高血压，占 67%。FBS、HbA1c、SUA、Cr、Chol、LDL、HDL 和 TG 的血清水平分别为 191.47 ± 71.66 mg/dL、7.94 ± 1.21 mg/dL、5.65 ± 1.95 mg/dL、0.94 ± 0.16 mg/dL、167.28 ± 45.22 mg/dL、95.91 ± 37.03 mg/dL、39.78 ± 10.44 mg/dL 和 186.75 ± 76.65 mg/dL。只有 UA 与 TG 水平有显著关系（P < 0.05）。
