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肝癌维持性血液透析患者合并肺肿瘤栓塞。

Pulmonary tumor embolism in a maintenance hemodialysis patient with hepatocellular carcinoma.

机构信息

Department of Nephrology, The First Hospital of HeBei Medical University, No.89 East DongGang Road, ShiJiaZhuang, 050030, People's Republic of China.

Graduate School of HeBei Medical University, No.386 East ZhongShan Boulevard, ShiJiaZhuang, 050030, People's Republic of China.

出版信息

CEN Case Rep. 2024 Apr;13(2):121-124. doi: 10.1007/s13730-023-00810-w. Epub 2023 Jul 25.

Abstract

Patients with chronic kidney disease are already at an increased risk for pulmonary embolism, since loss of renal function rendered a procoagulant state. Further, malignant tumor is a well-established risk factor for pulmonary thromboembolism. Alternatively, occlusion of the pulmonary vasculature by tumor cells per se and associated thrombi may mimic thromboembolic disease. By comparison, however, report of pulmonary tumor embolism (PTE) in patients on maintenance hemodialysis (MHD) is exceedingly rare. A less vigilant clinician may have otherwise treated this situation as fluid overload or thromboembolic disorder. We herein described in an MHD patient such an unusual case of PTE, which was diagnosed by contrast-enhanced CT and PET/CT. As such, our work may expand the knowledge reserve of dialysis staffs about this rare complication of malignancy.

摘要

患有慢性肾病的患者已经处于肺栓塞的高风险中,因为肾功能丧失导致了促凝状态。此外,恶性肿瘤是肺血栓栓塞症的一个明确的危险因素。相反,肿瘤细胞本身阻塞肺血管和相关血栓可能会模拟血栓栓塞性疾病。然而,相比之下,维持性血液透析(MHD)患者的肺肿瘤栓塞(PTE)报告极为罕见。如果临床医生不够警惕,可能会将这种情况误诊为液体超负荷或血栓栓塞性疾病。在此,我们描述了一例 MHD 患者中这种不常见的 PTE 病例,通过增强 CT 和 PET/CT 进行了诊断。因此,我们的工作可能会扩展透析工作人员对这种恶性肿瘤罕见并发症的知识储备。

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Pulmonary tumor embolism: A retrospective study over a 30-year period.肺肿瘤栓塞:一项为期 30 年的回顾性研究。
PLoS One. 2021 Aug 11;16(8):e0255917. doi: 10.1371/journal.pone.0255917. eCollection 2021.
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Pulmonary embolism in patients with CKD and ESRD.慢性肾脏病和终末期肾病患者的肺栓塞。
Clin J Am Soc Nephrol. 2012 Oct;7(10):1584-90. doi: 10.2215/CJN.00250112. Epub 2012 Jul 26.

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