Cherdak M A, Mkhitaryan E A
Pirogov Russian National Research Medical University, Moscow, Russia.
Russian Clinical and Research Center of Gerontology Pirogov - Russian National Research Medical University, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(7):124-129. doi: 10.17116/jnevro2023123071124.
Postcovid syndrome (PCS) is a complex multifactorial clinical condition that is a frequent complication of COVID-19. The development of PCS does not depend on the severity of the initial infectious disease, it has a pronounced effect on the quality of life and is characterized by a tendency to a protracted course. In the context of the ongoing COVID-19 pandemic, the emergence of new variants of the SARS-CoV-2 virus, it is important to develop common approaches to the diagnosis and management of patients suffering from this medical condition. The review presents current data on the epidemiology, pathogenesis, clinical presentation, and diagnosis of the PCS. The approaches to therapy of PCS are discussed, as well as the role of Cortexin, taking into account both theoretical and accumulated clinical data.
新冠后综合征(PCS)是一种复杂的多因素临床病症,是新冠病毒病(COVID-19)常见的并发症。PCS的发生并不取决于初始感染性疾病的严重程度,它对生活质量有显著影响,其特点是病程往往迁延不愈。在当前COVID-19大流行、严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒新变种不断出现的背景下,制定针对患有这种病症患者的诊断和管理的通用方法非常重要。本综述介绍了关于PCS的流行病学、发病机制、临床表现和诊断的当前数据。文中讨论了PCS的治疗方法,以及考虑到理论和积累的临床数据的情况下,Cortexin的作用。