Servicio de Pediatría.
Facultativos Especialistas de Área de Pediatría, Unidad de Oncohematología Infantil.
Bol Med Hosp Infant Mex. 2023;80(Supl 1):82-86. doi: 10.24875/BMHIM.22000122.
Takayasu arteritis is a large-vessel vasculitis which affects large-caliber elastic arteries, primarily the aorta and its main branches. It mainly affects women between 20-30 years, so it is rare in children.
We describe the case of a 15-year-old female who was followed up since she was 9 years old due to celiac disease. At the age of 13, anaemia of chronic disorders associated to elevated C-reactive protein and erythrocyte sedimentation were detected. The patient remained asymptomatic. After excluding other diseases, we requested a positron emission computed tomography (PET-CT); lesions compatible with large-vessel vasculitis were detected. Cardiology evaluation showed an aneurysm in the right coronary artery. Angio-CT suggested Takayasu type III arteritis.
The delay in the diagnosis of Takayasu arteritis in pediatric patients is quite common. In this case, we have found phase II lesions, with no previous phase I symptoms. However, PET-CT allowed the diagnosis of vasculitis, key to the diagnosis of the patient.
大动脉炎是一种大血管炎,主要影响大动脉的弹性,主要是主动脉及其主要分支。它主要发生在 20-30 岁的女性,因此在儿童中很少见。
我们描述了一例 15 岁女性的病例,她从 9 岁开始就因腹腔疾病而接受随访。13 岁时,检测到与 C 反应蛋白和红细胞沉降率升高相关的慢性疾病性贫血。患者无症状。排除其他疾病后,我们要求进行正电子发射计算机断层扫描(PET-CT);检测到与大血管炎相符的病变。心脏病学评估显示右冠状动脉动脉瘤。血管造影 CT 提示 Takayasu Ⅲ型大动脉炎。
儿科患者大动脉炎的诊断延迟较为常见。在这种情况下,我们发现了二期病变,而没有之前的一期症状。然而,PET-CT 可诊断血管炎,这是诊断患者的关键。