Fanni Salvatore C, Febi Maria, Colligiani Leonardo, Volpi Federica, Ambrosini Ilaria, Tumminello Lorenzo, Aghakhanyan Gayane, Aringhieri Giacomo, Cioni Dania, Neri Emanuele
Department of Translational Research, Academic Radiology, University of Pisa, Pisa, Italy.
Front Radiol. 2023 Apr 17;3:1141499. doi: 10.3389/fradi.2023.1141499. eCollection 2023.
The aim of this systematic review was to evaluate the state of the art of radiomics in testicular imaging by assessing the quality of radiomic workflow using the Radiomics Quality Score (RQS) and the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). A systematic literature search was performed to find potentially relevant articles on the applications of radiomics in testicular imaging, and 6 final articles were extracted. The mean RQS was 11,33 ± 3,88 resulting in a percentage of 31,48% ± 10,78%. Regarding QUADAS-2 criteria, no relevant biases were found in the included papers in the patient selection, index test, reference standard criteria and flow-and-timing domain. In conclusion, despite the publication of promising studies, radiomic research on testicular imaging is in its very beginning and still hindered by methodological limitations, and the potential applications of radiomics for this field are still largely unexplored.
本系统评价的目的是通过使用放射组学质量评分（RQS）和诊断准确性研究质量评估-2（QUADAS-2）来评估放射组学在睾丸成像中的技术现状，评估放射组学工作流程的质量。进行了系统的文献检索，以查找有关放射组学在睾丸成像中应用的潜在相关文章，并提取了6篇最终文章。RQS的平均值为11.33±3.88，百分比为31.48%±10.78%。关于QUADAS-2标准，纳入论文在患者选择、索引测试、参考标准标准以及流程和时间领域均未发现相关偏倚。总之，尽管发表了一些有前景的研究，但睾丸成像的放射组学研究尚处于起步阶段，仍受到方法学限制的阻碍，放射组学在该领域的潜在应用仍 largely unexplored。（注：“largely unexplored”直译为“很大程度上未被探索”，这里可灵活处理为“在很大程度上仍未得到充分探索”等通顺表述，但按要求不能添加解释，所以保留原文）
