局部晚期头颈癌预处理患者的生活质量及其相关因素：泰国的一项横断面研究。
Quality of life and its correlates in pretreatment patients with locally advanced head and neck cancer: A cross-sectional study in Thailand.
作者信息
Pimvichai Sirinya, Matchim Yaowarat, Sinthusake Tanadej, Wongkalasin Kiratiya
机构信息
Faculty of Nursing, Thammasat University, Pathum Thani, Thailand.
Maha Vajiralongkorn Thanyaburi Hospital, Department of Medical Services, Ministry of Public Health, Thailand.
出版信息
Belitung Nurs J. 2023 Jun 26;9(3):244-252. doi: 10.33546/bnj.2621. eCollection 2023.
BACKGROUND
Locally advanced head and neck cancer (LAHNC) can significantly impact the quality of life of patients in various ways. However, several factors can contribute to the decrease in quality of life. In Thailand, there is limited knowledge about the factors that affect the quality of life of patients with LAHNC before they receive treatment.
OBJECTIVE
This study aimed to examine the correlations between Palliative Performance Scale (PPS), family income, body mass index (BMI), age, comorbidity index, and the quality of life of patients with LAHNC before they undergo treatment.
METHODS
A correlational cross-sectional study was conducted, and data were collected from 94 pretreatment patients with LAHNC who were admitted to a cancer center in central Thailand using purposive sampling. The data collection instruments included a demographic data form, a medical record form, the Charlson Comorbidity Index (CCI), the Palliative Performance Scale (PPS), and the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N) version 4. Descriptive statistics, Pearson's correlation, and Spearman's rank correlation were used to analyze the data.
RESULTS
All study participants completed the questionnaire. The results showed that the overall quality of life of the patients was moderate. PPS, family income, and body mass index were moderately positively correlated with quality of life ( = 0.494, <0.01; = 0.420, <0.01; = 0.339, <0.01, respectively). Age had a moderate negative correlation with quality of life ( = -0.596, <0.01), while comorbidity was not significantly associated with quality of life.
CONCLUSION
The quality of life of patients with LAHNC before treatment was associated with various factors, including PPS, family income, body mass index, and age. These findings highlight the importance of nutritional support before treatment and the need for social support, especially for older adult patients, to improve their quality of life. The results of this study can be valuable for nurses in developing care programs that enhance the quality of life for patients with LAHNC during the pretreatment phase.
背景
局部晚期头颈癌（LAHNC）会在多个方面显著影响患者的生活质量。然而，有几个因素会导致生活质量下降。在泰国，对于影响LAHNC患者治疗前生活质量的因素了解有限。
目的
本研究旨在探讨姑息治疗表现量表（PPS）、家庭收入、体重指数（BMI）、年龄、合并症指数与LAHNC患者治疗前生活质量之间的相关性。
方法
进行了一项相关性横断面研究，采用目的抽样法从泰国中部一家癌症中心收治的94例LAHNC治疗前患者中收集数据。数据收集工具包括人口统计学数据表、病历表、查尔森合并症指数（CCI）、姑息治疗表现量表（PPS）以及癌症治疗功能评估-头颈（FACT-H&N）第4版。使用描述性统计、Pearson相关性分析和Spearman秩相关性分析对数据进行分析。
结果
所有研究参与者均完成了问卷。结果显示患者的总体生活质量为中等。PPS、家庭收入和体重指数与生活质量呈中度正相关（分别为r = 0.494，P <0.01；r = 0.420，P <0.01；r = 0.339，P <0.01）。年龄与生活质量呈中度负相关（r = -0.596，P <0.01），而合并症与生活质量无显著相关性。
结论
LAHNC患者治疗前的生活质量与多种因素相关，包括PPS、家庭收入、体重指数和年龄。这些发现凸显了治疗前营养支持的重要性以及社会支持的必要性，尤其是对于老年患者，以改善他们的生活质量。本研究结果对于护士制定提高LAHNC患者治疗前阶段生活质量的护理计划具有重要价值。
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