• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

代谢相关脂肪性肝病与多囊卵巢综合征的关联。

The Interlink Between Metabolic-Associated Fatty Liver Disease and Polycystic Ovary Syndrome.

机构信息

Obesity and Digestive Disease Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, col. Toriello Guerra, Mexico City C.P. 14050, Mexico.

Obesity and Digestive Disease Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, col. Toriello Guerra, Mexico City C.P. 14050, Mexico.

出版信息

Endocrinol Metab Clin North Am. 2023 Sep;52(3):533-545. doi: 10.1016/j.ecl.2023.01.005. Epub 2023 Mar 15.

DOI:10.1016/j.ecl.2023.01.005
PMID:37495343
Abstract

Polycystic ovary syndrome (PCOS) affects around 10% of women in the reproductive age group and is characterized by ovulatory dysfunction, hyperandrogenism, and/or polycystic ovarian morphology. PCOS is highly associated with metabolic-associated fatty liver disease (MAFLD) as both diseases share common risk factors. At the time of diagnosis of PCOS, screening for MAFLD is necessary because most patients with MAFLD are asymptomatic. The importance of early detection of MAFLD in patients with PCOS is that a timely intervention in patients with steatosis or steatohepatitis can reduce the probability of liver disease progression.

摘要

多囊卵巢综合征(PCOS)影响了大约 10%的育龄期女性,其特征为排卵功能障碍、高雄激素血症和/或多囊卵巢形态。PCOS 与代谢相关脂肪性肝病(MAFLD)高度相关,因为这两种疾病有共同的危险因素。在诊断 PCOS 时,筛查 MAFLD 是必要的,因为大多数 MAFLD 患者无症状。在 PCOS 患者中早期发现 MAFLD 的重要性在于,对脂肪变性或脂肪性肝炎患者进行及时干预可以降低肝病进展的概率。

相似文献

1
The Interlink Between Metabolic-Associated Fatty Liver Disease and Polycystic Ovary Syndrome.代谢相关脂肪性肝病与多囊卵巢综合征的关联。
Endocrinol Metab Clin North Am. 2023 Sep;52(3):533-545. doi: 10.1016/j.ecl.2023.01.005. Epub 2023 Mar 15.
2
Hepatic steatosis in women with polycystic ovary syndrome.多囊卵巢综合征女性的肝脂肪变性。
BMC Endocr Disord. 2023 Sep 26;23(1):207. doi: 10.1186/s12902-023-01456-6.
3
Hepatokines: the missing link in the development of insulin resistance and hyperandrogenism in PCOS?肝分泌因子:多囊卵巢综合征胰岛素抵抗和高雄激素血症发病机制中的缺失环节?
Hormones (Athens). 2023 Dec;22(4):715-724. doi: 10.1007/s42000-023-00487-x. Epub 2023 Sep 14.
4
Nonalcoholic Fatty Liver Disease in Patients with Polycystic Ovary Syndrome.多囊卵巢综合征患者的非酒精性脂肪性肝病。
Curr Pharm Des. 2018;24(38):4593-4597. doi: 10.2174/1381612825666190117100751.
5
Non-alcoholic fatty liver disease is associated with hyperandrogenism in women with polycystic ovary syndrome.非酒精性脂肪性肝病与多囊卵巢综合征妇女的高雄激素血症有关。
Sci Rep. 2023 Aug 17;13(1):13397. doi: 10.1038/s41598-023-39428-4.
6
Evidence that non-alcoholic fatty liver disease and polycystic ovary syndrome are associated by necessity rather than chance: a novel hepato-ovarian axis?非酒精性脂肪性肝病与多囊卵巢综合征必然相关而非偶然相关的证据:一种新的肝-卵巢轴?
Endocrine. 2016 Feb;51(2):211-21. doi: 10.1007/s12020-015-0640-8. Epub 2015 May 30.
7
Nonalcoholic fatty liver disease in women with polycystic ovary syndrome.多囊卵巢综合征女性中的非酒精性脂肪性肝病
Endocrine. 2020 Jan;67(1):1-8. doi: 10.1007/s12020-019-02085-7. Epub 2019 Sep 19.
8
Nonalcoholic fatty liver disease and polycystic ovary syndrome.非酒精性脂肪性肝病与多囊卵巢综合征
World J Gastroenterol. 2014 Jul 14;20(26):8351-63. doi: 10.3748/wjg.v20.i26.8351.
9
Metabolic consequences of obesity and insulin resistance in polycystic ovary syndrome: diagnostic and methodological challenges.多囊卵巢综合征中肥胖和胰岛素抵抗的代谢后果:诊断和方法学挑战。
Nutr Res Rev. 2017 Jun;30(1):97-105. doi: 10.1017/S0954422416000287. Epub 2017 Feb 22.
10
Insulin resistance and hyperandrogenism drive steatosis and fibrosis risk in young females with PCOS.胰岛素抵抗和高雄激素血症会增加年轻多囊卵巢综合征女性发生脂肪变性和肝纤维化的风险。
PLoS One. 2017 Nov 21;12(11):e0186136. doi: 10.1371/journal.pone.0186136. eCollection 2017.

引用本文的文献

1
Baicalin mitigates polycystic ovary syndrome‑associated non‑alcoholic fatty liver disease by inhibiting the AR/SREBP1 axis.黄芩苷通过抑制AR/SREBP1轴减轻多囊卵巢综合征相关的非酒精性脂肪性肝病。
Int J Mol Med. 2025 Nov;56(5). doi: 10.3892/ijmm.2025.5630. Epub 2025 Sep 12.
2
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.二甲双胍通过激活Ethe1/Keap1/PINK1通路减轻多囊卵巢综合征中的肝脏代谢功能障碍。
Int J Biol Sci. 2025 May 21;21(8):3505-3526. doi: 10.7150/ijbs.104778. eCollection 2025.
3
Transcriptome analysis of early embryonic development in a mouse model of polycystic ovary syndrome.
多囊卵巢综合征小鼠模型早期胚胎发育的转录组分析
Front Cell Dev Biol. 2025 May 2;13:1554437. doi: 10.3389/fcell.2025.1554437. eCollection 2025.
4
The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease.亚太肝脏研究协会代谢功能障碍相关脂肪性肝病诊断和管理临床实践指南
Hepatol Int. 2025 Apr;19(2):261-301. doi: 10.1007/s12072-024-10774-3. Epub 2025 Feb 27.
5
Clustering of > 145,000 symptom logs reveals distinct pre, peri, and menopausal phenotypes.超过145,000份症状记录的聚类分析揭示了不同的绝经前、围绝经期和绝经后表型。
Sci Rep. 2025 Jan 3;15(1):640. doi: 10.1038/s41598-024-84208-3.
6
Metabolic Dysfunction-associated Fatty Liver Disease: An Urgent Call for Global Action.代谢功能障碍相关脂肪性肝病:全球行动的紧急呼吁。
touchREV Endocrinol. 2024 Apr;20(1):5-9. doi: 10.17925/EE.2023.20.1.1. Epub 2023 Nov 8.