伊朗新冠肺炎重症监护病房患者的C反应蛋白、D-二聚体、红细胞沉降率和肌钙蛋白
C-reactive protein, D-dimer, erythrocyte sedimentation rate, and troponin in intensive care unit patients with COVID-19 in Iran.
作者信息
Salehi Hassan, Pakzad Bahram, Salehi Marzieh, Abbasi Saeed, Salehi Mohammad Mahdi, Naeini Maryam Kazemi
机构信息
Infectious Diseases and Tropical Medicine Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Internal Medicine, Division of Rheumatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2023 Jun 28;28:56. doi: 10.4103/jrms.jrms_352_22. eCollection 2023.
BACKGROUND
The coronavirus disease 2019 (COVID-19) pandemic in Iran has led to a lack of intensive care unit (ICU) facilities. This study examines C-reactive protein (CRP), D-dimer, erythrocyte sedimentation rate (ESR), and troponin in ICU patients with COVID-19 in comparison to COVID-19 patients admitted to the wards in Iran.
MATERIALS AND METHODS
In a case-control study, troponin, CRP, ESR, and D-dimer were compared in the case samples of 109 COVID-19 patients admitted to the ICU, and in the control group, 140 COVID-19 patients admitted to the wards.
RESULTS
The mean of CRP ( < 0.001) and D-dimer ( < 0.001) was higher, whereas troponin ( < 0.001) was lower in patients admitted to the ICU, but no significant difference was observed between the values of ESR ( = 0.292) in the two groups.
CONCLUSION
This study showed that the values of CRP and D-dimer were higher in patients admitted to the ICU, but no significant difference was observed between the values of ESR in the two groups.
背景
伊朗的2019冠状病毒病（COVID-19）大流行导致重症监护病房（ICU）设施短缺。本研究对伊朗入住ICU的COVID-19患者与入住普通病房的COVID-19患者的C反应蛋白（CRP）、D-二聚体、红细胞沉降率（ESR）和肌钙蛋白进行了检测。
材料与方法
在一项病例对照研究中，对109例入住ICU的COVID-19患者的病例样本与140例入住普通病房的COVID-19患者对照组的肌钙蛋白、CRP、ESR和D-二聚体进行了比较。
结果
入住ICU的患者CRP（<0.001）和D-二聚体（<0.001）的平均值较高，而肌钙蛋白（<0.001）较低，但两组ESR值（=0.292）之间未观察到显著差异。
结论
本研究表明，入住ICU的患者CRP和D-二聚体值较高，但两组ESR值之间未观察到显著差异。
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