Kobayashi Mariko, Akiyama Shintaro, Narasaka Toshiaki, Kobayashi Katsumasa, Yamauchi Atsushi, Yamada Atsuo, Omori Jun, Ikeya Takashi, Aoyama Taiki, Tominaga Naoyuki, Sato Yoshinori, Kishino Takaaki, Ishii Naoki, Sawada Tsunaki, Murata Masaki, Takao Akinari, Mizukami Kazuhiro, Kinjo Ken, Fujimori Shunji, Uotani Takahiro, Fujita Minoru, Sato Hiroki, Suzuki Sho, Hayasaka Junnosuke, Funabiki Tomohiro, Kinjo Yuzuru, Mizuki Akira, Kiyotoki Shu, Mikami Tatsuya, Gushima Ryosuke, Fujii Hiroyuki, Fuyuno Yuta, Gunji Naohiko, Toya Yosuke, Narimatsu Kazuyuki, Manabe Noriaki, Nagaike Koji, Kinjo Tetsu, Sumida Yorinobu, Funakoshi Sadahiro, Kobayashi Kiyonori, Matsuhashi Tamotsu, Komaki Yuga, Tsuchiya Kiichiro, Kaise Mitsuru, Nagata Naoyoshi
Division of Endoscopic Center University of Tsukuba Hospital Tsukuba Japan.
Department of Gastroenterology University of Tsukuba Tsukuba Japan.
JGH Open. 2023 Jul 12;7(7):487-496. doi: 10.1002/jgh3.12936. eCollection 2023 Jul.
While short and long attachment caps are available for colonoscopy, it is unclear which type is more appropriate for stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the performance of short long caps in acute hematochezia diagnoses and outcomes.
We selected 6460 patients who underwent colonoscopy with attachment caps from 10 342 acute hematochezia cases in the CODE BLUE-J study. We performed propensity score matching (PSM) to balance baseline characteristics between short and long cap users. Then, the proportion of definitive or presumptive bleeding etiologies found on the initial colonoscopy and SRH identification rates were compared. We also evaluated rates of blood transfusions, interventional radiology, or surgery, as well as the rate of rebleeding and mortality within 30 days after the initial colonoscopy.
A total of 3098 patients with acute hematochezia (1549 short cap and 1549 long cap users) were selected for PSM. The rate of colonic diverticular bleeding (CDB) diagnosis was significantly higher in long cap users ( = 0.006). While the two groups had similar rates of the other bleeding etiologies, the frequency of unknown etiologies was significantly lower in long cap users ( < 0.001). The rate of SRH with active bleeding was significantly higher in long cap users ( < 0.001). Other clinical outcomes did not differ significantly.
Compared to that with short caps, long cap-assisted colonoscopy is superior for the diagnosis of acute hematochezia, especially CDB, and the identification of active bleeding.
虽然结肠镜检查有短附件帽和长附件帽可供使用,但目前尚不清楚哪种类型更适合用于急性便血中近期出血痕迹(SRH)的识别。本研究旨在比较短附件帽和长附件帽在急性便血诊断及结果方面的表现。
我们从CODE BLUE-J研究中的10342例急性便血病例中选取了6460例行结肠镜检查并使用附件帽的患者。我们进行了倾向评分匹配(PSM)以平衡短附件帽使用者和长附件帽使用者之间的基线特征。然后,比较初次结肠镜检查时确定或推测的出血病因比例以及SRH识别率。我们还评估了输血、介入放射学或手术的发生率,以及初次结肠镜检查后30天内再出血和死亡率。
共3098例急性便血患者(1549例短附件帽使用者和1549例长附件帽使用者)被选入PSM。长附件帽使用者中结肠憩室出血(CDB)的诊断率显著更高(=0.006)。虽然两组其他出血病因的发生率相似,但长附件帽使用者中病因不明的频率显著更低(<0.001)。长附件帽使用者中伴有活动性出血的SRH发生率显著更高(<0.001)。其他临床结果无显著差异。
与短附件帽相比,长附件帽辅助的结肠镜检查在急性便血尤其是CDB的诊断以及活动性出血的识别方面更具优势。