Bronte-Moreno Olaia, González-Barcala Francisco-Javier, Muñoz-Gall Xavier, Pueyo-Bastida Ana, Ramos-González Jacinto, Urrutia-Landa Isabel
Department of Respiratory Medicine, Hospital Universitario Galdakao, Vizcaya, Spain.
Department of Respiratory Medicine, Hospital Clínico Universitario de Santiago de Compostela, Spain.
Open Respir Arch. 2023 Jan 3;5(2):100229. doi: 10.1016/j.opresp.2022.100229. eCollection 2023 Apr-Jun.
Asthma is the most common chronic respiratory disease and a major public health problem. Although the causal relationship between air pollution and asthma remains controversial, a large number of studies have provided increasingly consistent evidence of the involvement of air pollutants in asthma onset and exacerbations. We conducted a keyword search-based literature review using PubMed, Scopus and Web of Science databases for studies with titles or abstracts containing predefined terms. This narrative review discusses the current evidence on the pathological effects of pollution throughout life and the mechanisms involved in the onset, development, and exacerbation of asthma, and presents current measures and interventions for pollution damage control. Further global efforts are still needed to improve air quality.
哮喘是最常见的慢性呼吸道疾病,也是一个重大的公共卫生问题。尽管空气污染与哮喘之间的因果关系仍存在争议,但大量研究越来越一致地证明空气污染物参与了哮喘的发作和加重。我们使用PubMed、Scopus和Web of Science数据库进行了基于关键词搜索的文献综述,以查找标题或摘要中包含预定义术语的研究。本叙述性综述讨论了目前关于一生当中污染的病理影响以及哮喘发作、发展和加重所涉及机制的证据,并介绍了当前控制污染损害的措施和干预手段。仍需要全球进一步努力来改善空气质量。