Department of Pharmacy, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, 135001, Haryana, India.
Department of Pharmacy, GD Goenka University, Gurugram, Haryana, India.
Antiinflamm Antiallergy Agents Med Chem. 2023;22(1):1-9. doi: 10.2174/1871523022666230727094250.
Inflammatory Bowel Disease (IBD), including Ulcerative Colitis (UC) and Crohn's Disease (CD), is a continuously increasing healthcare problem mainly characterized by chronic relapsing intestinal inflammation. The common symptoms of UC and CD include inflammation, diarrhea, abdominal pain, bleeding, and weight loss. IBD is generally caused by an interaction between genetic and environmental or microbial factors that influence the body's immune response and is responsible for digestive disorders and inflammation of the intestinal tract. However, a complete understanding of the pathophysiology and work-up of IBD is necessary to ensure appropriate treatment for the management of this complex disease. This review enlightens herbal therapeutics and drug delivery systems for the management of IBD, and thus provides new insights into this field and facilitates access to new treatments.
炎症性肠病(IBD),包括溃疡性结肠炎(UC)和克罗恩病(CD),是一个不断增加的医疗保健问题,主要特征为慢性复发性肠道炎症。UC 和 CD 的常见症状包括炎症、腹泻、腹痛、出血和体重减轻。IBD 通常是由遗传和环境或微生物因素相互作用引起的,这些因素影响身体的免疫反应,导致消化道紊乱和肠道炎症。然而,为了确保对这种复杂疾病进行适当的治疗,需要全面了解 IBD 的病理生理学和检查方法。本综述阐述了草药治疗学和药物传递系统在 IBD 管理中的应用,为该领域提供了新的见解,并为新的治疗方法提供了便利。