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翻修率高和假体周围股骨远端骨折行股骨远端置换术后死亡率:德国关节置换注册中心(EPRD)分析。

High revision rates and mortality after distal femoral replacement for periprosthetic distal femoral fractures: analysis from the German Arthroplasty Registry (EPRD).

机构信息

University Center of Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.

German Arthroplasty Registry (EPRD), Berlin, Germany.

出版信息

Eur J Orthop Surg Traumatol. 2024 Jan;34(1):331-338. doi: 10.1007/s00590-023-03582-2. Epub 2023 Jul 27.

DOI:10.1007/s00590-023-03582-2
PMID:37498352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10771596/
Abstract

PURPOSE

This study was initiated to analyze the outcome after distal femoral replacement (DFR) for periprosthetic distal femoral fractures (PDFF).

METHODS

Data from the German Arthroplasty Registry (EPRD) were analyzed. A total of 626 patients could be identified with a DFR for PDFF. Mean age was 78.8 years, and 84.2% were female. Revisions and mortality were analyzed and compared with patient groups with a similar procedure (revision total knee arthroplasty) or similar general condition (fracture total hip arthroplasty, hip hemiarthroplasty). Matched-pair-analyses were performed.

RESULTS

Within one year after surgery, 13.2% of the patients had died and further 9.4% were revised. Within four years, 32.7% had died and 19.7% were revised. Revisions were nearly twice as high as in the comparison groups. Periprosthetic infection (PJI) was the most frequent cause for revision, resulting in a PJI rate of 12.8%, which was lower in the comparison groups. Mortality after DFR was as similar high as after fracture hip arthroplasty.

CONCLUSION

PDFF are a serious injury, and the necessary surgical treatment has a high risk of complications. Every third patient after DFR for PDFF had died and every fifth patient needed revision within 4 years after surgery. Efforts should be undertaken to provide optimal treatment to these high-risk patients to reduce unfavorable outcomes.

LEVEL OF EVIDENCE

III.

REGISTRATION OF CLINICAL TRIALS

As this is a registry-derived study of data of the German Arthroplasty Registry (EPRD), no registration was performed.

摘要

目的

本研究旨在分析股骨远端置换(DFR)治疗股骨假体周围远端骨折(PDFF)的结果。

方法

对德国关节置换登记处(EPRD)的数据进行分析。共确定了 626 例接受 DFR 治疗 PDFF 的患者。平均年龄为 78.8 岁,84.2%为女性。分析了翻修和死亡率,并与接受类似手术(翻修全膝关节置换术)或相似一般情况(骨折全髋关节置换术、髋关节半髋关节置换术)的患者组进行了比较。进行了配对分析。

结果

术后 1 年内,13.2%的患者死亡,9.4%的患者接受了翻修。4 年内,32.7%的患者死亡,19.7%的患者接受了翻修。翻修率几乎是对照组的两倍。假体周围感染(PJI)是翻修的最常见原因,导致 PJI 发生率为 12.8%,低于对照组。DFR 后的死亡率与骨折髋关节置换术相似。

结论

PDFF 是一种严重的损伤,必要的手术治疗并发症风险很高。每 3 例接受 DFR 治疗 PDFF 的患者中就有 1 例死亡,每 5 例患者中有 1 例在术后 4 年内需要翻修。应努力为这些高风险患者提供最佳治疗,以降低不良后果。

证据水平

III。

临床试验注册

由于这是对德国关节置换登记处(EPRD)数据的基于登记的研究,因此未进行注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/baa3d1d00dee/590_2023_3582_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/06a8a7238a17/590_2023_3582_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/57222ab1c89b/590_2023_3582_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/baa3d1d00dee/590_2023_3582_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/06a8a7238a17/590_2023_3582_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/47e5e50b31db/590_2023_3582_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/424f0ad1999a/590_2023_3582_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/513b62c14850/590_2023_3582_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/57222ab1c89b/590_2023_3582_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/10771596/baa3d1d00dee/590_2023_3582_Fig6_HTML.jpg

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本文引用的文献

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Epidemiology and characteristics of femoral periprosthetic fractures : data from the characteristics, outcomes and management of periprosthetic fracture service evaluation (COMPOSE) cohort study.股骨假体周围骨折的流行病学和特征:来自假体周围骨折服务评估(COMPOSE)队列研究的特征、结果和管理数据。
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用于治疗膝关节 native 骨折的股骨远端置换术:来自澳大利亚矫形协会全国关节置换登记处的结果。
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Distal Femoral Replacement for Periprosthetic Fractures After TKA: Australian Orthopaedic Association National Joint Replacement Registry Review.全膝关节置换术后假体周围骨折的股骨远端置换:澳大利亚矫形协会全国关节置换登记研究回顾。
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