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原发性单吻合口十二指肠空肠旁路术加袖状胃切除术(SADI-S)与袖状胃切除术至 SADI 转换:患病率和安全性的比较研究。

Primary single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) versus sleeve gastrectomy to SADI conversions: a comparison study of prevalence and safety.

机构信息

Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Surg Endosc. 2023 Nov;37(11):8682-8689. doi: 10.1007/s00464-023-10305-5. Epub 2023 Jul 27.

DOI:10.1007/s00464-023-10305-5
PMID:37500921
Abstract

BACKGROUND

Conversion from sleeve gastrectomy (SG) to single anastomosis duodeno-ileal bypass (SADI) is becoming increasingly common, but data regarding safety is of these conversions is scarce. As such, the objective of this study was to compare the 30-day rate of serious complications and mortality of primary SADI (p-SADI-S) with SG to SADI (SG-SADI) conversions.

METHODS

This retrospective cohort study analyzed the MBSAQIP database. Patients undergoing p-SADI-S and SG-SADI were included. Data collection was limited to 2020 and 2021. A multivariable logistic regression analysis was performed between groups to determine if SG-SADI was an independent predictor of 30-day serious complications or mortality.

RESULTS

A total of 783 patients were included in this study, 488 (62.3%) underwent p-SADI-S and 295 (37.6%) underwent SG-SADI. The mean body mass index (BMI) at the time of surgery was lower in the SG-SADI cohort (45.1 vs 51.4 kg/m, p < 0.001). Indications for revision in the SG-SADI cohort included weight recurrence (50.8%), inadequate weight loss (41.0%), other (3.0%), GERD (2.7%), and persistent comorbidities (2.5%). SG-SADI had longer operative times (156.7 vs 142.1 min, p < 0.001) and was not associated with a higher rate of serious complications (5.7 vs 6.9%, p = 0.508) compared to p-SADI-S. p-SADI-S was associated with a higher rate of pneumonia (1.2 vs 0.0%, p < 0.001), and SG-SADI was not correlated with higher rates of reoperation (3.0 vs 3.2%, p = 0.861), readmission (5.4 vs 5.5%, p = 0.948) and death (0.0 vs 0.2%, p = 0.437). On multivariable analysis, SG-SADI was not independently predictive of serious complications (OR 0.81, 95% CI 0.43 to 1.52, p = 0.514) when adjusting for age, sex, BMI, comorbidities, and operative time.

CONCLUSIONS

The prevalence of SG-SADI is high, representing 37.6% of SADI-S procedures. Conversion from sleeve to SADI, is safe, and as opposed to other studies of revisional bariatric surgery, has similar 30-day complication rates to primary SADI-S.

摘要

背景

袖状胃切除术(SG)到单吻合口十二指肠空肠旁路术(SADI)的转换越来越常见,但关于这些转换安全性的数据却很少。因此,本研究的目的是比较原发性 SADI(p-SADI-S)与 SG 到 SADI(SG-SADI)转换的 30 天严重并发症和死亡率。

方法

这是一项回顾性队列研究,分析了 MBSAQIP 数据库。纳入接受 p-SADI-S 和 SG-SADI 的患者。数据收集仅限于 2020 年和 2021 年。对两组进行多变量逻辑回归分析,以确定 SG-SADI 是否是 30 天严重并发症或死亡率的独立预测因素。

结果

本研究共纳入 783 例患者,其中 488 例(62.3%)接受 p-SADI-S,295 例(37.6%)接受 SG-SADI。SG-SADI 组手术时的平均体重指数(BMI)较低(45.1 与 51.4 kg/m2,p<0.001)。SG-SADI 组的修订指征包括体重复发(50.8%)、减重不足(41.0%)、其他(3.0%)、胃食管反流病(2.7%)和持续合并症(2.5%)。SG-SADI 的手术时间较长(156.7 与 142.1 min,p<0.001),但与 p-SADI-S 相比,严重并发症发生率无差异(5.7%与 6.9%,p=0.508)。p-SADI-S 与肺炎发生率较高相关(1.2%与 0.0%,p<0.001),而 SG-SADI 与再次手术率(3.0%与 3.2%,p=0.861)、再入院率(5.4%与 5.5%,p=0.948)和死亡率(0.0%与 0.2%,p=0.437)无关。多变量分析显示,调整年龄、性别、BMI、合并症和手术时间后,SG-SADI 不是严重并发症的独立预测因素(OR 0.81,95%CI 0.43 至 1.52,p=0.514)。

结论

SG-SADI 的患病率较高,占 SADI-S 手术的 37.6%。袖状胃切除术到 SADI 的转换是安全的,与其他减重手术的再手术研究相比,其 30 天并发症发生率与原发性 SADI-S 相似。

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