Clinical Epidemiology Division, Department of Medicine (Solna), Karolinska Institutet, Maria Aspmans Gata 30A, SE-171 64, Stockholm, Sweden.
Unit of Gastroenterology, Department of Medicine (Huddinge), Karolinska Institutet, Stockholm, Sweden.
Obes Surg. 2023 Sep;33(9):2841-2850. doi: 10.1007/s11695-023-06753-6. Epub 2023 Jul 27.
Ways to motivate and support patients in being physically active after bariatric surgery are needed. This trial was aimed at evaluating the effect of using a smartphone application targeting physical activity during 12 weeks on moderate-to-vigorous physical activity (MVPA, primary outcome) and secondary outcomes of inactivity, light physical activity (LPA), body mass index (BMI), and percent total weight loss (%TWL) after bariatric surgery.
Data from a randomized controlled trial comprising 146 patients (79.5% women) undergoing bariatric surgery was analyzed. Mean age and BMI pre-surgery were 40.9 years and 40.5 kg/m, respectively. Participants were randomized 1:1 to an intervention or a control group. Physical activity and body weight were objectively measured at baseline pre-surgery and post-surgery follow-ups after 6 weeks (weight only), 18 weeks, 6 months, and 1 year. Linear mixed models were fitted to assess longitudinal differences in outcomes between the groups.
A significant effect of the intervention (group-by-time interaction 16.2, 95% CI 3.5 to 28.9) was seen for MVPA at 18 weeks; the intervention group had increased their MVPA since baseline, while the control group had decreased their MVPA. The control group had lowered their BMI approximately 1 kg/m more than the intervention group at follow-up after 18 weeks and 12 months, yet, mean BMI did not differ between the groups. No intervention effect was seen on inactivity, LPA, or %TWL.
Our results indicate that use of a smartphone application targeting physical activity may have the potential to promote short-term MVPA post bariatric surgery.
Clinicaltrials.gov : NCT03480464.
需要寻找激励和支持肥胖症患者术后积极运动的方法。本试验旨在评估在 12 周内使用针对身体活动的智能手机应用程序对中度至剧烈体力活动(MVPA,主要结局)和术后非活动、低强度体力活动(LPA)、体重指数(BMI)和总体重减轻百分比(%TWL)的次要结局的影响。
对一项包含 146 名(79.5%为女性)接受肥胖症手术患者的随机对照试验数据进行了分析。术前平均年龄和 BMI 分别为 40.9 岁和 40.5kg/m2。参与者以 1:1 的比例随机分为干预组和对照组。在术前基线和术后 6 周(仅体重)、18 周、6 个月和 1 年的随访中,对身体活动和体重进行了客观测量。使用线性混合模型评估组间结局的纵向差异。
干预组在 18 周时 MVPA 出现显著的组间时间交互效应(16.2,95%CI3.5 至 28.9);干预组自基线以来增加了 MVPA,而对照组则减少了 MVPA。在 18 周和 12 个月的随访中,对照组的 BMI 比干预组降低了约 1kg/m,但两组的 BMI 平均值没有差异。在非活动、LPA 或%TWL 方面,干预没有效果。
我们的结果表明,使用针对身体活动的智能手机应用程序可能具有促进肥胖症手术后短期 MVPA 的潜力。
Clinicaltrials.gov:NCT03480464。