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二维灌注分析在评估单侧颈内动脉狭窄中的应用价值

Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis.

作者信息

Yoshikawa Akifumi, Uno Takehiro, Nambu Iku, Kamide Tomoya, Misaki Kouichi, Nakada Mitsutoshi

机构信息

Department of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, Japan.

出版信息

J Neuroendovasc Ther. 2021;15(9):583-588. doi: 10.5797/jnet.oa.2020-0132. Epub 2021 Jan 14.

DOI:10.5797/jnet.oa.2020-0132
PMID:37501751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10370787/
Abstract

OBJECTIVE

We investigated the usefulness of 2D-perfusion analysis for the evaluation of cerebral blood flow in unilateral cervical internal carotid artery stenosis.

METHODS

We conducted a 2D-perfusion analysis during cerebral angiography and I-iodoamphetamine (IMP) single photon emission computed tomography (SPECT) for unilateral cervical internal carotid artery stenosis without contralateral stenosis. The relationship between the ratio of the lesion side to the normal side in the parameters obtained by 2D-perfusion and the value calculated by stereotactic extraction estimation (SEE) analysis of SPECT was statistically examined.

RESULTS

The ratios of the lesion side to the normal side regarding the peak arrival time (AT; time to peak [TTP]) of the contrast agent and the mean filling time (mean transit time [MTT]) of the contrast agent in 2D-perfusion significantly correlated with the area of Stage II and increase ratio (I.R) ≤30% in the SEE analysis (p = 0.002, 0.003).

CONCLUSION

2D-perfusion analysis can be used to estimate the extent of impaired cerebrovascular reserve (CVR) area in unilateral internal carotid artery stenosis.

摘要

目的

我们研究了二维灌注分析在评估单侧颈内动脉狭窄时脑血流方面的实用性。

方法

我们对无对侧狭窄的单侧颈内动脉狭窄患者在脑血管造影和I - 碘安非他明（IMP）单光子发射计算机断层扫描（SPECT）期间进行了二维灌注分析。对二维灌注获得的参数中病变侧与正常侧的比值和SPECT立体定向提取估计（SEE）分析计算的值之间的关系进行了统计学检验。

结果

二维灌注中造影剂的峰值到达时间（AT；达峰时间[TTP]）和造影剂的平均充盈时间（平均通过时间[MTT]）的病变侧与正常侧比值与SEE分析中的II期面积和增加率（I.R）≤30%显著相关（p = 0.002，0.003）。

结论

二维灌注分析可用于估计单侧颈内动脉狭窄时脑血管储备（CVR）受损区域的范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/24fb622f1ad1/jnet-15-583-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/eb332ecd51e7/jnet-15-583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/c1d8cf405104/jnet-15-583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/3c49131d7105/jnet-15-583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/24fb622f1ad1/jnet-15-583-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/eb332ecd51e7/jnet-15-583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/c1d8cf405104/jnet-15-583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/3c49131d7105/jnet-15-583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c699/10370787/24fb622f1ad1/jnet-15-583-g004.jpg

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