Libell Joshua L, Balar Aneri B, Libell David P, Joseph Joe T, Hogg Jeffery P, Lakhani Dhairya A, Khan Musharaf
School of Medicine, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA.
Department of Radiology, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA.
Radiol Case Rep. 2023 Jul 22;18(10):3442-3447. doi: 10.1016/j.radcr.2023.06.043. eCollection 2023 Oct.
Schwannomas are rare nerve sheath tumors that can occur throughout the body, and are symptomatic based on location, size, and impingement on adjacent structures. These tumors are often benign lesions and occur sporadically or from genetic conditions such as neurofibromatosis. Schwannomas may arise from peripheral nerves, gastrointestinal nerves, spinal nerve roots and cranial nerves. Facial nerve schwannomas arise from cranial nerve VII, commonly involving the geniculate ganglion, labyrinthine segment, and internal auditory canal. While small lesions are asymptomatic, larger lesions can cause facial nerve paralysis, and facial spasms. Lesions in the internal auditory canal can cause hearing loss, tinnitus, vertigo, and otalgia. High-resolution CT imaging and MRI imaging are useful for distinguishing between other pathologies that arise from the same region. High-resolution CT scans can show bony degeneration of nearby structures such as the labyrinth or ossicles. MRI imaging shows hypo intensity on T1 imaging, and hyperintensity on T2 imaging. On T1 postcontrast, enhancement can be homogenous or heterogeneous with cystic degeneration if the lesion is large. Nodular enhancement is commonly seen on facial nerve schwannomas within the internal auditory canal. Vestibular schwannomas involving CN VIII are more common, and appear similar to facial nerve schwannomas, but can be distinguished apart due to growth in the geniculate ganglion and/or the labyrinthine segment. Management of asymptomatic or mild lesions is typically conservative with follow up imaging, and surgery for larger lesions. Here, we present a case of a facial nerve schwannoma in a 57-year-old woman.
施万细胞瘤是一种罕见的神经鞘瘤,可发生于全身,其症状取决于肿瘤的位置、大小以及对相邻结构的压迫情况。这些肿瘤通常为良性病变,可散发出现,也可由神经纤维瘤病等遗传疾病引发。施万细胞瘤可起源于周围神经、胃肠神经、脊神经根和颅神经。面神经施万细胞瘤起源于颅神经VII,通常累及膝状神经节、迷路段和内耳道。较小的病变通常无症状,而较大的病变可导致面神经麻痹和面肌痉挛。内耳道的病变可引起听力丧失、耳鸣、眩晕和耳痛。高分辨率CT成像和MRI成像有助于鉴别同一区域出现的其他病变。高分辨率CT扫描可显示附近结构如迷路或听小骨的骨质退变。MRI成像在T1加权像上呈低信号,在T2加权像上呈高信号。在T1加权像增强扫描时,如果病变较大,可出现均匀或不均匀强化,并伴有囊性退变。内耳道内的面神经施万细胞瘤通常可见结节状强化。累及CN VIII的前庭神经鞘瘤更为常见,其表现与面神经施万细胞瘤相似,但由于其在膝状神经节和/或迷路段生长,可与之鉴别。对于无症状或轻度病变,通常采用保守治疗并进行随访成像,对于较大病变则进行手术治疗。在此,我们报告一例57岁女性面神经施万细胞瘤的病例。