Reis da Silva Alexandre, Basto Rita, Correia Barbosa Renato, Viana Ana Rita, Teixeira Carla
Ophthalmology Department, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, Matosinhos, PRT.
Cureus. 2023 Jun 25;15(6):e40955. doi: 10.7759/cureus.40955. eCollection 2023 Jun.
This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thoracic CT scan confirmed a nodular mass in the right hilus, suggesting bronchogenic neoplastic process. A pleural biopsy demonstrated malignant neoplasia with characteristics of adenocarcinoma, and immunohistochemistry was positive for thyroid transcription factor 1 (TTF-1). These findings emphasize the critical role of ophthalmological examinations in early detection and intervention, as choroidal tissue is highly susceptible to metastasis, particularly from breast and lung cancers. Additionally, the poor prognosis associated with metastatic lung cancer underscores the urgency for prompt action.
本病例报告介绍了一位视力下降的82岁女性。临床和多模态评估显示黄斑病变隆起伴脉络膜增厚。荧光素血管造影和光学相干断层扫描（OCT）显示了脉络膜转移的特征性模式。胸部CT扫描证实右肺门有一个结节状肿块，提示支气管源性肿瘤病变。胸膜活检显示为具有腺癌特征的恶性肿瘤，免疫组化甲状腺转录因子1（TTF-1）呈阳性。这些发现强调了眼科检查在早期发现和干预中的关键作用，因为脉络膜组织极易发生转移，尤其是来自乳腺癌和肺癌的转移。此外，转移性肺癌的预后较差凸显了迅速采取行动的紧迫性。
