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阿替卡因或丁香酚用于不可逆性牙髓炎患牙急诊冠髓切断术后止痛的疗效:一项随机临床试验

Efficacy of Articaine or Eugenol for Pain Relief after Emergency Coronal Pulpotomy in Teeth with Irreversible Pulpitis: A Randomized Clinical Trial.

作者信息

De Grado Gabriel Fernandez, Clément Bourdin, Florence Fioretti, Anne-Marie Musset, Damien Offner

机构信息

I INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, CRBS, 1 Rue Emile Boeckel, 67084 Strasbourg, France.

Université de Strasbourg, Faculté de Chirurgie Dentaire, 8 rue Ste Elisabeth, 67000 Strasbourg, France.

出版信息

Dent J (Basel). 2023 Jul 11;11(7):167. doi: 10.3390/dj11070167.

DOI:10.3390/dj11070167
PMID:37504233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10377881/
Abstract

UNLABELLED

Irreversible pulpitis is an extremely painful dental pathology. Its emergency treatment, pulpotomy, should include the use of a pulp dressing in the pulp chamber until the final treatment. Various antalgic products have been suggested as efficient medications to relieve the patient's pain and are commonly used, but data for scientific validation are scarce.

OBJECTIVE

We evaluated the efficacy of articaine or eugenol in the diminution of pain after pulpotomy.

DESIGN

We included 100 patients with irreversible pulpitis and evaluated their initial pain levels. Pain was measured using a 0-10 numeric rating scale. After treatment through pulpotomy, we randomized them into two groups using either articaine or eugenol as a pulp dressing and evaluated their pain level at 1, 3 and 7 days.

RESULTS

Initial pain levels were severe (7.53). The use of painkillers was not associated with lower levels of pain. Both treatments showed great efficiency on day 1, with stronger efficiency of eugenol than articaine, showing a decrease of 6.24 versus 4.89 ( = 0.025). Both treatments were efficient, whatever the age or sex of the patient, the initial pain level, and the causal tooth.

CONCLUSION

Pulpotomy is an efficient way to relieve pain, using either articaine or eugenol. When choosing a pulp dressing, eugenol should be the first choice.

摘要

未标注

不可逆性牙髓炎是一种极其疼痛的牙科病理状况。其紧急治疗方法——牙髓切断术,在进行最终治疗前应包括在牙髓腔使用牙髓敷料。各种镇痛产品已被建议作为缓解患者疼痛的有效药物且被普遍使用,但缺乏科学验证的数据。

目的

我们评估了阿替卡因或丁香酚在牙髓切断术后减轻疼痛方面的疗效。

设计

我们纳入了100例不可逆性牙髓炎患者并评估了他们最初的疼痛水平。使用0至10的数字评分量表测量疼痛。通过牙髓切断术治疗后,我们将他们随机分为两组,分别使用阿替卡因或丁香酚作为牙髓敷料,并在第1、3和7天评估他们的疼痛水平。

结果

最初的疼痛水平严重(7.53)。使用止痛药与较低的疼痛水平无关。两种治疗在第1天均显示出高效,丁香酚的效果强于阿替卡因,疼痛减轻程度分别为6.24和4.89(P = 0.025)。无论患者的年龄或性别、最初的疼痛水平以及患牙情况如何,两种治疗均有效。

结论

牙髓切断术是一种使用阿替卡因或丁香酚缓解疼痛的有效方法。在选择牙髓敷料时,丁香酚应是首选。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b569/10377881/cb1a33319487/dentistry-11-00167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b569/10377881/44bd7725d00d/dentistry-11-00167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b569/10377881/cb1a33319487/dentistry-11-00167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b569/10377881/44bd7725d00d/dentistry-11-00167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b569/10377881/cb1a33319487/dentistry-11-00167-g002.jpg

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