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蓝牙 iCOquit、piCO 与 Vitalograph 在评估成人戒烟起始者呼出气一氧化碳与标准罐方面的比较。

Comparison of the Bluetooth iCOquit, piCO, and Vitalograph for the assessment of breath carbon monoxide among adults initiating smoking cessation and standardized canisters.

机构信息

TSET Health Promotion Research Center, Stephenson Cancer Center, Oklahoma City, OK, United States.

TSET Health Promotion Research Center, Stephenson Cancer Center, Oklahoma City, OK, United States.

出版信息

Drug Alcohol Depend. 2023 Sep 1;250:110902. doi: 10.1016/j.drugalcdep.2023.110902. Epub 2023 Jul 22.

DOI:10.1016/j.drugalcdep.2023.110902
PMID:37506541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10529684/
Abstract

BACKGROUND

The Bluetooth iCOquit enables remote biochemical verification of smoking status, but its validity among adults attempting to quit smoking is unclear. This study 1) compared the iCOquit, piCO, and Vitalograph sensors to identify device-specific bias, 2) assessed the diagnostic accuracy of the iCOquit for the overall sample and within specific subgroups (sex, race, smoking rate, menthol use), and 3) assessed the validity of iCOquit readings against standardized CO canisters.

METHODS

iCOquit devices were tested with human breath samples from individuals seeking treatment for combustible tobacco use (N = 93) attending an in-person clinic visit. Participants provided breath samples via the iCOquit, piCO, and Vitalograph (order randomized). iCOquit devices were also tested using 5 and 10 parts per million (ppm) canisters.

RESULTS

The iCOquit underestimated CO and categorized more participants as abstinent relative to the other CO sensors with human breath samples. The results suggested the iCOquit could not be used interchangeably with the other CO devices. Using a cut-off of < 6 ppm, the diagnostic accuracy of the iCOquit (specificity = 94%; sensitivity = 85%) did not vary across demographic/smoking subgroups. Canister tests with the iCOquit suggested good precision (< 1 ppm).

CONCLUSIONS

The iCOquit is an affordable option for the remote measurement of CO that provides a reasonably accurate assessment of smoking status of those attempting to quit smoking using abstinence cut-off criteria of < 6 ppm. However, compared to other CO monitors, the iCOquit may underestimate CO, thereby increasing error in assessing abstinence.

摘要

背景

蓝牙 iCOquit 可远程生化验证吸烟状态,但对于试图戒烟的成年人来说,其有效性尚不清楚。本研究 1)比较了 iCOquit、piCO 和 Vitalograph 传感器,以确定设备特异性偏差,2)评估了 iCOquit 对整个样本和特定亚组(性别、种族、吸烟率、薄荷醇使用)的诊断准确性,3)评估了 iCOquit 读数与标准化 CO 罐的有效性。

方法

使用正在接受治疗的可燃烟草使用者(N=93)的人体呼吸样本对 iCOquit 设备进行测试,他们参加了现场诊所就诊。参与者通过 iCOquit、piCO 和 Vitalograph(随机顺序)提供呼吸样本。还使用 5 和 10 ppm 罐对 iCOquit 设备进行了测试。

结果

与其他 CO 传感器相比,iCOquit 低估了 CO 并将更多参与者归类为戒烟者。结果表明,iCOquit 不能与其他 CO 设备互换使用。使用 < 6 ppm 的截断值,iCOquit 的诊断准确性(特异性 = 94%;敏感性 = 85%)在人口统计学/吸烟亚组中没有差异。使用 iCOquit 的罐测试表明精度良好(< 1 ppm)。

结论

iCOquit 是一种经济实惠的远程 CO 测量选项,对于使用 < 6 ppm 的戒烟截断标准评估试图戒烟者的吸烟状态,提供了相当准确的评估。然而,与其他 CO 监测器相比,iCOquit 可能会低估 CO,从而增加评估戒烟的误差。

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