Sorrentino Thomas A, Sutaria Saheel, Butler Patrick, Burnett Daniel, Bennett-Guerrero Elliott
Department of Surgery, University of California, San Francisco, San Francisco, California, United States.
Gravitas Medical, San Francisco, California, United States.
Nutrition. 2023 Nov;115:112144. doi: 10.1016/j.nut.2023.112144. Epub 2023 Jun 30.
The aim of this study was to validate the ability of a novel, impedance-based platform for nasogastric feeding tube (FT) insertion to correctly predict intragastric FT placement in healthy individuals with and without acid suppression medication.
Ten patients underwent successive placement of 8, 10, and 12 French FTs with the final intragastric position predicted using an impedance-based algorithm and verified with an abdominal x-ray. Study procedures were repeated after patients received a proton pump inhibitor (PPI) for 3 d.
Nasogastric FTs with embedded electrodes spaced along the distal 31 cm of the tubes were placed with the final insertion depth determined by an algorithm integrating impedance and other physiologic parameters. Sixty FT (30 pre-PPI and 30 post-PPI) insertions were performed. The algorithm-predicted location was confirmed as intragastric in all insertions by post-placement abdominal x-ray. For all tube sizes and those with and without PPIs, the impedance at electrodes within the esophagus was significantly higher than at electrodes in the stomach (P < 0.01). As a secondary objective to assess the use of gastric aspirate pH to determine location, gastric aspirate could only be obtained in 30% of insertions. The mean gastric pH was 6.9 (SD 0.6) in patients taking PPIs.
A novel platform for real-time assistance with nasogastric FT placement confirmation correctly determined intragastric FT location as confirmed by abdominal x-ray (standard of care) in all 60 insertions. Gastric pH measurements were difficult to obtain and unreliable for intragastric FT placement confirmation in patients taking acid suppression medication.
本研究旨在验证一种基于阻抗的新型鼻胃饲管(FT)插入平台在有或无抑酸药物的健康个体中正确预测胃内FT放置位置的能力。
10例患者先后插入8号、10号和12号法国FT,最终胃内位置使用基于阻抗的算法预测,并通过腹部X光片验证。患者接受质子泵抑制剂(PPI)治疗3天后重复研究程序。
沿导管远端31 cm间隔嵌入电极的鼻胃FT,其最终插入深度由整合阻抗和其他生理参数的算法确定。共进行了60次FT插入(30次PPI治疗前和30次PPI治疗后)。放置后腹部X光片证实所有插入的算法预测位置均在胃内。对于所有导管尺寸以及使用和未使用PPI的情况,食管内电极处的阻抗显著高于胃内电极处(P<0.01)。作为评估使用胃抽吸物pH值确定位置的次要目标,仅在30%的插入操作中获得了胃抽吸物。服用PPI的患者胃平均pH值为6.9(标准差0.6)。
一种用于实时辅助确认鼻胃FT放置位置的新型平台在所有60次插入操作中均正确确定了胃内FT位置,经腹部X光片(护理标准)证实。对于服用抑酸药物的患者,难以获得胃pH值测量结果,且其对于确认胃内FT放置位置不可靠。