Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, M48, Karolinska Universitetssjukhuset Huddinge, 14186, Stockholm, Sweden.
Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Trials. 2023 Jul 29;24(1):483. doi: 10.1186/s13063-023-07509-4.
Cognitive behavioral therapy (CBT) is a moderately efficacious treatment for hoarding disorder (HD), with most individuals remaining symptomatic after treatment. The Joining Forces Trial will evaluate whether 10 weeks of in-home decluttering can significantly augment the outcomes of group CBT.
A randomized controlled trial of in-home decluttering augmentation of group CBT for HD. Adult participants with HD (N = 90) will receive 12 weeks of protocol-based group CBT for HD. After group CBT, participants will be randomized to either 10 weeks of in-home decluttering led by a social services team or a waitlist. The primary endpoint is 10 weeks post-randomization. The primary outcome measures are the self-reported Saving Inventory-Revised and the blind assessor-rated Clutter Image Rating. Participants on the waitlist will cross over to receive the in-home decluttering intervention after the primary endpoint. Data will be analyzed according to intention-to-treat principles. We will also evaluate the cost-effectiveness of this intervention from both healthcare and societal perspectives.
HD is challenging to treat with conventional psychological treatments. We hypothesize that in-home decluttering sessions carried out by personnel in social services will be an efficacious and cost-effective augmentation strategy of group CBT for HD. Recruitment started in January 2021, and the final participant is expected to reach the primary endpoint in December 2024.
ClinicalTrials.gov NCT04712474. Registered on 15 January 2021.
认知行为疗法(CBT)是治疗囤积障碍(HD)的一种中度有效方法,但大多数患者在治疗后仍存在症状。“联合力量”试验将评估家庭杂物清理是否能显著增强团体认知行为治疗的效果。
一项针对团体认知行为治疗中家庭杂物清理增强的随机对照试验。患有 HD 的成年参与者(N=90)将接受为期 12 周的基于方案的团体认知行为治疗 HD。在团体 CBT 之后,参与者将被随机分配到家庭杂物清理 10 周或候补名单。主要终点是随机分组后 10 周。主要结果测量是自我报告的节省库存修订版和盲评估者评定的杂乱图像评分。候补名单上的参与者将在主要终点后交叉接受家庭杂物清理干预。数据将根据意向治疗原则进行分析。我们还将从医疗保健和社会角度评估这种干预的成本效益。
HD 用传统的心理治疗方法很难治疗。我们假设,由社会服务人员进行的家庭杂物清理会议将是团体认知行为治疗 HD 的一种有效且具有成本效益的增强策略。招募工作于 2021 年 1 月开始,预计最后一名参与者将于 2024 年 12 月达到主要终点。
ClinicalTrials.gov NCT04712474。于 2021 年 1 月 15 日注册。