Bansal G C, Sharma S P
Vet Parasitol. 1986 Aug;21(3):145-9. doi: 10.1016/0304-4017(86)90061-0.
Therapeutic and prophylactic efficacies of parvaquone and long-acting oxytetracycline were tested against Theileria annulata infection, induced by injecting a suspension of infected ground tick tissues (GUTS) into groups of 4 or 5 calves. This infection killed two of four control calves, while all the animals given a single intramuscular dose of 20 mg kg-1 parvaquone or long-acting oxytetracycline on the day of infection underwent mild reactions and recovered. Two separate doses of parvaquone of 10 mg kg-1 administered on the first and second days of fever protected four out of five calves. All the recovered animals from both treated and control groups resisted a homologous challenge with GUTS on Day 45 post-infection which killed three out of four susceptible unimmunized control calves.
对小剂量喹酮和长效土霉素针对环形泰勒虫感染的治疗和预防效果进行了测试。通过向4或5头小牛组注射感染的地蜱组织（GUTS）悬液诱导感染。这种感染导致4头对照小牛中的2头死亡，而在感染当天单次肌肉注射20 mg kg-1小剂量喹酮或长效土霉素的所有动物出现轻微反应并康复。在发热的第一天和第二天分别给予10 mg kg-1的小剂量喹酮，保护了5头小牛中的4头。来自治疗组和对照组的所有康复动物在感染后第45天抵抗了GUTS的同源攻击，此次攻击导致4头易感未免疫对照小牛中的3头死亡。
