Bassan Tiziana, Pastor Josep, Agulla Beatriz, Jornet Oriol, Martorell Jaume
Fundació Hospital Clínic Veterinari, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain.
Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain.
Animals (Basel). 2023 Jul 23;13(14):2389. doi: 10.3390/ani13142389.
Thromboelastography (TEG) is a viscoelastic technique that allows the examination of both cellular and plasma protein clotting factors. Thromboelastography helps to investigate the underlying coagulopathy and to monitor therapeutic modalities. Although viscoelastic techniques have been used in human and veterinary medicine, reference ranges in pet rabbits are missing. The objective of this study is to establish the reference-range values of TEG parameters in healthy pet rabbits. 24 healthy pet rabbits of different breeds were included: 16 crossbreeds, four Californians, two lops, one lionhead, and one angora. Four rabbits were less than one year old and 20 were older than one year. Twelve rabbits were neutered females, 10 neutered males, and two were intact females. Health status was assessed through a physical examination, a complete blood work, and a coagulation profile. A TEG 5000 Thromboelastograph Hemostasis System was used with kaolin-activated citrated whole blood. All samples were analysed 30 min postextraction. The TEG reference ranges were reaction time (R) 1.4-6.9 min; clot formation time (K) 0.8-2.2 min; α angle 65.8-82.2 degrees; maximal amplitude (MA) 53.7-73.5 mm; measure of clot strength/firmness (G-value) 5796.6-13,885.9 dyn/cm; and percentage of clot lysis in 30 min (LY30%) 0-41.5%. This study provides the reference ranges of TEG in pet rabbits.
血栓弹力图（TEG）是一种粘弹性技术，可用于检测细胞和血浆蛋白凝血因子。血栓弹力图有助于调查潜在的凝血病并监测治疗方式。尽管粘弹性技术已应用于人类和兽医学，但宠物兔的参考范围尚缺。本研究的目的是建立健康宠物兔TEG参数的参考范围值。纳入了24只不同品种的健康宠物兔：16只杂交兔、4只加利福尼亚兔、2只垂耳兔、1只狮头兔和1只安哥拉兔。4只兔子年龄小于1岁，20只兔子年龄大于1岁。12只为绝育雌性兔，10只为绝育雄性兔，2只为未绝育雌性兔。通过体格检查、全血细胞分析和凝血指标评估健康状况。使用TEG 5000血栓弹力图止血系统和高岭土激活的枸橼酸盐全血。所有样本在提取后30分钟进行分析。TEG参考范围为：反应时间（R）1.4 - 6.9分钟；凝血形成时间（K）0.8 - 2.2分钟；α角65.8 - 82.2度；最大振幅（MA）53.7 - 73.5毫米；凝血强度/硬度测量值（G值）5796.6 - 13885.9达因/厘米；30分钟内凝血溶解百分比（LY30%）0 - 41.5%。本研究提供了宠物兔TEG的参考范围。
