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丹麦全国队列研究:功能性癫痫患儿及青少年的治疗情况

Treatment Provided in Children and Adolescents with Functional Seizures-A Danish Nationwide Cohort.

作者信息

Sørensen Nana Brandborg, Nielsen René Ernst, Christensen Ann-Eva, Kjeldsen Mikkel Kristian, Rask Charlotte Ulrikka, Christensen Jakob, Hansen Anne Sofie

机构信息

Unit for Psychiatric Research, Psychiatry, Aalborg University Hospital, 9000 Aalborg, Denmark.

Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark.

出版信息

Children (Basel). 2023 Jul 14;10(7):1218. doi: 10.3390/children10071218.

DOI:10.3390/children10071218
PMID:37508715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10378534/
Abstract

BACKGROUND

Functional seizures (FS) are episodes of paroxysmal involuntary movements and altered consciousness without the typical changes in the electroencephalography as with epilepsy. A multidisciplinary approach is the golden standard in the treatment of FS. This study examined the cross-sectoral collaboration and treatment modalities provided to children and adolescents after a diagnosis of FS.

METHOD

A Danish nationwide cohort, consisting of 334 children and adolescents, aged 5-17 years, with a validated diagnosis of FS during the period 2004-2014 was studied. Medical record data were collected from diagnosing hospital departments. Management and treatment modalities from the time of diagnosis up to three months after diagnosis were explored.

RESULTS

The most used treatment modalities were psychoeducation ( = 289, 86.5%) and follow-up in outpatient care ( = 192, 70.6%). A cross-sectoral collaboration was initiated for a third of cases ( = 98, 29.3%). The most commonly provided treatment combination consisted of psychoeducation, follow-up in outpatient care and psychotherapy; however, only a few patients received this specific combination ( = 14, 4.2%).

CONCLUSIONS

The treatment applied was individualized and consisted of varying use of treatment modalities. Initiatives to curate clinical guidelines and implement a multidisciplinary treatment approach should be further explored to improve treatment for this young group of patients.

摘要

背景

功能性癫痫发作(FS)是阵发性不自主运动和意识改变的发作,脑电图无癫痫典型变化。多学科方法是FS治疗的金标准。本研究调查了FS诊断后为儿童和青少年提供的跨部门协作及治疗方式。

方法

对丹麦全国范围内一个队列进行研究,该队列由334名5至17岁儿童和青少年组成,他们在2004年至2014年期间经确诊为FS。从诊断医院科室收集病历数据。探究从诊断时到诊断后三个月的管理和治疗方式。

结果

最常用的治疗方式是心理教育(n = 289,86.5%)和门诊随访(n = 192, 70.6%)。三分之一的病例启动了跨部门协作(n = 98,29.3%)。最常提供的治疗组合包括心理教育、门诊随访和心理治疗;然而,只有少数患者接受了这种特定组合(n = 14,4.2%)。

结论

所采用的治疗是个体化的,包括不同治疗方式的使用。应进一步探索制定临床指南和实施多学科治疗方法的举措,以改善对这一年轻患者群体的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4773/10378534/116335554e0d/children-10-01218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4773/10378534/1bd9dce7881c/children-10-01218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4773/10378534/116335554e0d/children-10-01218-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4773/10378534/1bd9dce7881c/children-10-01218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4773/10378534/116335554e0d/children-10-01218-g002.jpg

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The effectiveness of psychological interventions for children and adolescents with non-epileptic seizures.心理干预对非癫痫性发作儿童和青少年的有效性。
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Paroxysmal Nonepileptic Events in a Pediatric Epilepsy Clinic.儿科癫痫诊所中的阵发性非癫痫性事件
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Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.精神性非癫痫性发作的心理治疗依从性与治疗结果。
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