Harvie Daniel Simon
IIMPACT in Health, Allied Health and Human Performance Unit, University of South Australia, Adelaide, SA 5000, Australia.
Brain Sci. 2023 Jul 12;13(7):1063. doi: 10.3390/brainsci13071063.
The sensorimotor incongruence theory proposes that certain instances of pain result from conflicts in the brain's sensorimotor networks. Indeed, injuries may cause abnormalities in afferent and cortical signaling resulting in such conflicts. Motion sickness also occurs in instances of incongruent sensorimotor data. It is possible that a sensory processing phenotype exists that predisposes people to both conditions.
The aim of this study was to investigate whether participants with chronic pain recall greater susceptibility to motion sickness before chronic pain onset.
Data were collected via an online LimeSurvey. A self-report tendency toward motion sickness was measured using the Motion Sickness Susceptibility Questionnaire. Group differences were analysed using analysis of covariance methods.
530 patients (low back pain, = 198; neck pain, = 59; whiplash-associated disorder, = 72; fibromyalgia syndrome, = 114; Migraine, = 41) and 165 pain-free controls were surveyed. ANCOVA analysis, using sex and anxiety as covariates, suggested that childhood motion sickness susceptibility scores differed by group (F = 2.55 (6, 615), = 0.019, (ηp2) = 0.024). Planned comparisons, with corrected -values, suggested that childhood motion sickness was not statistically greater for low back pain, rheumatoid arthritis, migraine, neck pain or whiplash-associated disorder (s > 0.05), although scores were on average 27%, 42%, 47%, 48% and 58% higher, respectively. Childhood susceptibility was statistically higher in people with FMS ( = 0.018), with scores on average 83% higher than controls. ANCOVA analysis, using sex and anxiety as covariates, suggested that adult motion sickness susceptibility scores did not differ by group (F = 1.86 (6, 613), = 0.086), although average scores were, on average, at least 33% higher in persistent pain groups.
According to retrospective reporting, greater susceptibility to motion sickness appears to pre-date persistent pain in some conditions. This supports the possibility that motion sickness and chronic pain may, in some cases, have overlapping mechanisms related to the handling of incongruent sensorimotor data.
感觉运动不一致理论认为，某些疼痛情况是由大脑感觉运动网络中的冲突引起的。事实上，损伤可能会导致传入和皮质信号异常，从而引发此类冲突。晕动病也会在感觉运动数据不一致的情况下发生。有可能存在一种感觉加工表型，使人们易患这两种疾病。
本研究旨在调查慢性疼痛患者在慢性疼痛发作前是否回忆起对晕动病的易感性更高。
通过在线LimeSurvey收集数据。使用晕动病易感性问卷测量晕动病的自我报告倾向。采用协方差分析方法分析组间差异。
对530名患者（腰痛患者198例；颈部疼痛患者59例；挥鞭样损伤相关疾病患者72例；纤维肌痛综合征患者114例；偏头痛患者41例）和165名无疼痛对照者进行了调查。以性别和焦虑作为协变量的协方差分析表明，儿童期晕动病易感性评分在不同组间存在差异（F = 2.55 (6, 615), p = 0.019, (ηp2) = 0.024）。经校正p值的计划比较表明，对于腰痛、类风湿性关节炎、偏头痛、颈部疼痛或挥鞭样损伤相关疾病，儿童期晕动病在统计学上并不更高（p > 0.），尽管分数分别平均高出27%、42%、47%、48%和58%。纤维肌痛综合征患者的儿童期易感性在统计学上更高（p = 0.018），分数平均比对照组高出83%。以性别和焦虑作为协变量的协方差分析表明，成人晕动病易感性评分在不同组间没有差异（F = 1.86 (6, 613), p = 0.086），尽管在持续性疼痛组中平均分数至少高出33%。
根据回顾性报告，在某些情况下，对晕动病的更高易感性似乎早于持续性疼痛出现。这支持了晕动病和慢性疼痛在某些情况下可能具有与处理不一致的感觉运动数据相关的重叠机制的可能性。
