Aquaro Giovanni Donato, Monastero Silvia, Todiere Giancarlo, Barison Andrea, De Gori Carmelo, Grigoratos Crysanthos, Parisella Maria Luisa, Faggioni Lorenzo, Cioni Dania, Lencioni Riccardo, Neri Emanuele
Academic Radiology Unit, Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.
Gabriele Monasterio CNR-Tuscany Foundation, 56127 Pisa, Italy.
Diagnostics (Basel). 2023 Jul 24;13(14):2461. doi: 10.3390/diagnostics13142461.
We sought to compare native T1 mapping to conventional late gadolinium enhancement (LGE) and T2-STIR techniques in a cohort of consecutive patients undergoing cardiac MRI (CMR). CMR was performed in 323 patients, 206 males (64%), mean age 54 ± 8 years, and in 27 age- and sex- matched healthy controls. In T2-STIR images, myocardial hyperintensity suggesting edema was found in 41 patients (27%). LGE images were positive in 206 patients (64%). T1 mapping was abnormal in 171 (49%). In 206 patients (64%), a matching between LGE and native T1 was found. T1 was abnormal in 32 out of 41 (78%) with edema in T2-STIR images. Overall, LGE and/or T2-STIR were abnormal in 209 patients, whereas native T1 was abnormal in 154 (52%). Conventional techniques and T1 mapping were concordant in 208 patients (64%). In 39 patients, T1 mapping was positive despite negative conventional techniques (12%). T1 mapping was able in conditions with diffuse myocardial damage such as cardiac amyloidosis, scleroderma, and Fabry disease (additive role in 42%). In contrast, T1 mapping was less effective in cardiac disease with regional distribution of myocardial damage such as myocardial infarction, HCM, and myocarditis. In conclusion, conventional LGE/T2-STIR and T1 mapping are complementary techniques and should be used together in every CMR examination.
我们试图在一组连续接受心脏磁共振成像（CMR）的患者中，比较天然T1 mapping与传统延迟钆增强（LGE）及T2-STIR技术。对323例患者（206例男性，占64%，平均年龄54±8岁）及27例年龄和性别匹配的健康对照者进行了CMR检查。在T2-STIR图像中，41例患者（27%）发现提示水肿的心肌高信号。LGE图像在206例患者（64%）中呈阳性。T1 mapping异常的有171例（49%）。在206例患者（64%）中，发现LGE与天然T1之间存在匹配。T2-STIR图像中有水肿的41例患者中，32例（78%）T1异常。总体而言，209例患者LGE和/或T2-STIR异常，而天然T1异常的有154例（52%）。传统技术与T1 mapping在208例患者（64%）中结果一致。在39例患者中，尽管传统技术结果为阴性，但T1 mapping呈阳性（12%）。T1 mapping在弥漫性心肌损伤的情况下，如心脏淀粉样变性、硬皮病和法布里病中有效（在42%的病例中起辅助作用）。相比之下，T1 mapping在心肌损伤呈局部分布的心脏病中，如心肌梗死、肥厚型心肌病和心肌炎中效果较差。总之，传统LGE/T2-STIR和T1 mapping是互补技术，应在每次CMR检查中联合使用。
