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抽脂治疗脂肪性水肿的患者报告结局

Patient-Reported Outcomes of Liposuction for Lipedema Treatment.

作者信息

Kirstein Fiona, Hamatschek Matthias, Knors Henning, Aitzetmueller-Klietz Marie-Luise, Aitzetmueller-Klietz Matthias, Wiebringhaus Philipp, Varnava Charalampos, Hirsch Tobias, Kueckelhaus Maximilian

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, Germany.

Plastic and Reconstructive Surgery, Institute of Musculoskeletal Medicine, Westfalian Wilhelms-University, 48149 Muenster, Germany.

出版信息

Healthcare (Basel). 2023 Jul 13;11(14):2020. doi: 10.3390/healthcare11142020.

Abstract

BACKGROUND

Lipedema, as a disabling and consequential disease, is gaining more awareness due to its potential omnipresence. Patients suffering from lipedema show a characteristic painful display of symmetric accumulations of adipose tissue. The combination of swelling, pain and decreased quality of life (QOL) is outstanding for the diagnosis. The aim of this study was to identify the effect of liposuction in terms of the QOL for patients and underline important factors of current and pending research regarding surgical therapy of lipoedema.

METHODS

Patients suffering from lipedema prior to and after receiving liposuction at our hospital were included in this study. Patients completed a lipedema-specific self-designed 50 item questionnaire: the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Patient Health Questionnaire 9 (PHQ-9). A linear mixed model was used for outcome analysis.

RESULTS

In total, 511 patients completed a questionnaire prior to the surgery at primary presentation to the hospital and a total number of 56 patients completed a questionnaire after liposuction. A total of 34 of these patients filled in both questionnaires prior to and after surgery. The general characteristics of the disease, such as daily symptoms and psychological health, pertinently improved after surgery.

CONCLUSIONS

Liposuction can have a general improving effect on the QOL of patients, both in private and professional life. Liposuction may currently be the most evident and promising method in the treatment of lipedema.

摘要

背景

脂肪性水肿作为一种致残性且后果严重的疾病,因其潜在的普遍性而日益受到关注。患有脂肪性水肿的患者表现出脂肪组织对称堆积的典型疼痛症状。肿胀、疼痛和生活质量(QOL)下降的综合表现是诊断该病的突出特征。本研究的目的是确定抽脂术对患者生活质量的影响,并强调当前和未来关于脂肪性水肿手术治疗研究的重要因素。

方法

本研究纳入了在我院接受抽脂术前后患有脂肪性水肿的患者。患者完成了一份专门设计的包含50个项目的脂肪性水肿问卷、世界卫生组织生活质量简表(WHOQOL-BREF)和患者健康问卷9(PHQ-9)。采用线性混合模型进行结果分析。

结果

共有511名患者在初次就诊于医院时手术前完成了问卷,共有56名患者在抽脂术后完成了问卷。其中共有34名患者在手术前后都填写了两份问卷。疾病的一般特征,如日常症状和心理健康状况,在手术后有显著改善。

结论

抽脂术对患者的生活质量在私人生活和职业生活方面都能产生总体改善作用。抽脂术目前可能是治疗脂肪性水肿最明显且最有前景的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30f/10379396/7bb4faf94555/healthcare-11-02020-g0A1.jpg

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