Maurina Matteo, Benedetti Alice, Stefanini Giulio, Condorelli Gianluigi, Collet Carlos, Zivelonghi Carlo, Smits Pieter C, Paradies Valeria
Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.
Cardio Center, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
J Clin Med. 2023 Jul 24;12(14):4864. doi: 10.3390/jcm12144864.
A considerable number of patients with angina or myocardial ischemia have no significant coronary artery disease on invasive angiography. In recent years, several steps towards a better comprehension of the pathophysiology of these conditions, angina or ischemia with non-obstructive coronary arteries (ANOCA/INOCA), have been made. Nevertheless, several gaps in knowledge still remain. This review is intended to provide a comprehensive overview of ANOCA and INOCA, with a particular focus on pathophysiology, recent diagnostic innovations, gaps in knowledge and treatment modalities.
相当一部分患有心绞痛或心肌缺血的患者在有创血管造影检查中并无明显的冠状动脉疾病。近年来，在更好地理解这些病症（非阻塞性冠状动脉性心绞痛/心肌缺血，ANOCA/INOCA）的病理生理学方面已经取得了一些进展。然而，在知识方面仍存在一些空白。本综述旨在全面概述ANOCA和INOCA，特别关注病理生理学、近期的诊断创新、知识空白和治疗方式。
