Department of Neurosciences, Institute of Human Anatomy, University of Padova, Via Gabelli 65, 35121 Padova, Italy.
Plastic and Reconstructive Surgery Unit, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Int J Mol Sci. 2023 Jul 18;24(14):11599. doi: 10.3390/ijms241411599.
The recent findings showed that the superficial fascia is a fibrous layer in the middle of hypodermis, richly innervated and vascularized, and more complex than so far demonstrated. This study showed the presence of mast cells in the superficial fascia of the human abdomen wall of three adult volunteer patients (mean age 42 ± 4 years; 2 females, 1 male), by Toluidine Blue and Safranin-O stains and Transmission Electron Microscopy. Mast cells are distributed among the collagen bundles and the elastic fibers, near the vessels and close to the nerves supplying the tissue, with an average density of 20.4 ± 9.4/mm. The demonstration of the presence of mast cells in the human superficial fascia highlights the possible involvement of the tissue in the inflammatory process, and in tissue healing and regeneration processes. A clear knowledge of this anatomical structure of the hypodermis is fundamental for a good comprehension of some fascial dysfunctions and for a better-targeted clinical practice.
最近的研究结果表明，浅筋膜是皮下组织中层的纤维层，富含神经和血管，比目前所展示的更为复杂。本研究通过甲苯胺蓝和番红 O 染色和透射电子显微镜，在三位成年志愿者患者（平均年龄 42 ± 4 岁；2 名女性，1 名男性）的人体腹壁浅筋膜中发现了肥大细胞。肥大细胞分布在胶原束和弹性纤维之间，靠近血管，靠近供应组织的神经，平均密度为 20.4 ± 9.4/mm。在人体浅筋膜中存在肥大细胞的证明突出了组织可能参与炎症过程以及组织愈合和再生过程。对皮下组织这种解剖结构的清晰认识，对于理解一些筋膜功能障碍和更好地针对临床实践至关重要。
