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1
Do black-box models of thermoregulation still have any research value? Contribution of system-theoretical models to the analysis of thermoregulation.体温调节的黑箱模型是否仍具有研究价值?系统理论模型对体温调节分析的贡献。
Yale J Biol Med. 1986 May-Jun;59(3):335-48.
2
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体温调节的黑箱模型是否仍具有研究价值?系统理论模型对体温调节分析的贡献。

Do black-box models of thermoregulation still have any research value? Contribution of system-theoretical models to the analysis of thermoregulation.

作者信息

Werner J

出版信息

Yale J Biol Med. 1986 May-Jun;59(3):335-48.

PMID:3751138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2590166/
Abstract

The aims and the usefulness of modelling the thermoregulatory system are outlined by demonstrating applications and results of simulation on different levels of complexity. It is shown that both very simple one-loop models and complex models based on spatially distributed parameters have contributed to a better understanding of the system, but that current issues primarily require the latter type. However, mathematical modelling must be performed in conjunction with experimental studies and must be adapted to the amount of basic physiological data. Future fields of modelling are the adaptive mechanisms and the interactions of systems.

摘要

通过展示不同复杂程度的模拟应用和结果,概述了热调节系统建模的目的和实用性。结果表明,非常简单的单环模型和基于空间分布参数的复杂模型都有助于更好地理解该系统,但当前的问题主要需要后者这种类型。然而,数学建模必须与实验研究相结合,并必须适应基础生理数据的数量。建模的未来领域是自适应机制和系统间的相互作用。