Dragomir Angela, Lupu Maria Alina, Lighezan Rodica, Paduraru Ana Alexandra, Olariu Tudor Rares
Discipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Clinical Laboratory, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania.
Life (Basel). 2023 Jul 17;13(7):1575. doi: 10.3390/life13071575.
(1) Background: infects approximately one third of the world's human population. The seroepidemiology of in cardiovascular patients is poorly discussed in the existing literature. We aimed to evaluate, for the first time, the seroprevalence of in cardiovascular patients from Western Romania. (2) Methods: Serologic testing to demonstrate the presence of antibodies was conducted in 256 patients with cardiovascular diseases and 261 matched blood donors. (3) Results: The overall seroprevalence of antibodies was 64.06% in patients with cardiovascular diseases and 52.88% in blood donors and tended to increase with age in both groups. The seroprevalence of antibodies was significantly higher in cardiovascular male patients (69.94%) compared to male blood donors (55.69%) ( = 0.006). When compared to the control group, a significantly higher prevalence of antibodies was found among patients with hypertension (82.35%; = 0.01) and unstable angina (67.56%; = 0.02). (4) Conclusions: This study brings new epidemiological information on the prevalence of in Romanian cardiovascular patients. seroprevalence was significantly higher in patients with hypertension and unstable angina, suggesting that individuals with these diagnoses may be more frequently infected with . This study may be a valuable starting point for further research to better evaluate the impact of exposure on patients with cardiovascular diseases.
(1) 背景：感染了全球约三分之一的人口。现有文献中对心血管疾病患者的血清流行病学讨论较少。我们旨在首次评估罗马尼亚西部心血管疾病患者中的血清流行率。(2) 方法：对256例心血管疾病患者和261名匹配的献血者进行血清学检测以证明抗体的存在。(3) 结果：心血管疾病患者中抗体的总体血清流行率为64.06%，献血者中为52.88%，两组均随年龄增长而升高。心血管男性患者中抗体的血清流行率（69.94%）显著高于男性献血者（55.69%）（P = 0.006）。与对照组相比，高血压患者（82.35%；P = 0.01）和不稳定型心绞痛患者（67.56%；P = 0.02）中抗体的流行率显著更高。(4) 结论：本研究提供了罗马尼亚心血管疾病患者中血清流行率的新流行病学信息。高血压和不稳定型心绞痛患者中的血清流行率显著更高，表明患有这些疾病的个体可能更频繁地感染。本研究可能是进一步研究的有价值起点，以更好地评估暴露对心血管疾病患者的影响。
