Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Center for Diagnosis and Study of Parasitic Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Medicina (Kaunas). 2022 Jan 30;58(2):208. doi: 10.3390/medicina58020208.
: High rates of infection with were found in psychiatric patients globally. In this study, we assessed for the first time the prevalence of infection in psychiatric patients and healthy individuals with no known psychiatric disorders in Western Romania. : The presence of specific IgG anti- antibodies was evaluated in 308 psychiatric patients and 296 control subjects using a chemiluminescence assay. : Overall, the seroprevalence of IgG antibodies was higher in psychiatric patients (67.86%; 209/308), compared with the control group (54.05%; 160/296) ( < 0.001). Our results revealed a significantly higher prevalence of antibodies among patients with schizophrenia (69.77%), organic (personality and behaviour) disorders (76.74%), and mental disorders concerning alcohol abuse (84.62%), compared with the control group ( = 0.009, = 0.005, = 0.043, respectively). : This study provides new and important information on the seroprevalence of in Romanian psychiatric patients and may serve for further scientific research regarding the status of infection in patients with psychiatric disorders.
在全球范围内，精神科患者的感染率都很高。在这项研究中，我们首次评估了罗马尼亚西部地区精神科患者和无已知精神疾病的健康个体中 感染的流行率。
使用化学发光测定法评估了 308 名精神科患者和 296 名对照者的特异性 IgG 抗- 抗体。
总体而言，与对照组（54.05%；160/296）相比，精神科患者（67.86%；209/308）的 IgG 抗体血清阳性率更高（<0.001）。我们的结果显示，与对照组相比，精神分裂症（69.77%）、器质性（人格和行为）障碍（76.74%）和酒精滥用相关精神障碍（84.62%）患者的 抗体阳性率显著更高（=0.009，=0.005，=0.043，分别）。
这项研究提供了罗马尼亚精神科患者中 感染血清阳性率的新的重要信息，可能有助于进一步研究精神障碍患者中 感染状况。
