Infection in Patients with Psychiatric Disorders from Western Romania.

: High rates of infection with were found in psychiatric patients globally. In this study, we assessed for the first time the prevalence of infection in psychiatric patients and healthy individuals with no known psychiatric disorders in Western Romania. : The presence of specific IgG anti- antibodies was evaluated in 308 psychiatric patients and 296 control subjects using a chemiluminescence assay. : Overall, the seroprevalence of IgG antibodies was higher in psychiatric patients (67.86%; 209/308), compared with the control group (54.05%; 160/296) ( < 0.001). Our results revealed a significantly higher prevalence of antibodies among patients with schizophrenia (69.77%), organic (personality and behaviour) disorders (76.74%), and mental disorders concerning alcohol abuse (84.62%), compared with the control group ( = 0.009, = 0.005, = 0.043, respectively). : This study provides new and important information on the seroprevalence of in Romanian psychiatric patients and may serve for further scientific research regarding the status of infection in patients with psychiatric disorders.