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放射治疗诱发的心房黏液瘤:一例报告及文献综述

Radiotherapy-Induced Atrial Myxoma: A Case Report and Literature Review.

作者信息

Shalata Walid, Massalha Ismaell, Ishay Shlomo Yaron, Chernomordikova Elena, Jama Ashraf Abu, Rouvinov Keren, Dudnik Yulia, Yakobson Alexander

机构信息

The Legacy Heritage Center & Dr. Larry Norton Institute, Soroka Medical Center, Ben Gurion University, Beer Sheva 84105, Israel.

Department of Cardio-Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

出版信息

Life (Basel). 2023 Jul 19;13(7):1585. doi: 10.3390/life13071585.

DOI:10.3390/life13071585
PMID:37511961
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10381263/
Abstract

In this particular case study, we present a 66-year-old male who was diagnosed with an atrial myxoma eight years after receiving treatment for non-small cell lung cancer. The patient underwent chemo-radiotherapy (mediastinal area) in 2012 to address stage III-A adenocarcinoma of the lung. During follow-up imaging in 2020, a left atrial mass displaying characteristic features of a cardiac myxoma was detected. Upon reviewing a computed tomographic (CT) scan from 2017 within the previously irradiated mediastinal region, the cardiac mass was retrospectively identified. The surgical excision of the cardiac mass was performed, and a subsequent pathological examination confirmed the diagnosis of myxoma. To the best of our knowledge, this is the first reported case of a left atrial myxoma in a patient previously treated for adenocarcinoma of the lung and the first instance of an atrial myxoma occurring in a site that had undergone prior radiation therapy.

摘要

在这个特定的病例研究中,我们介绍了一位66岁男性,他在接受非小细胞肺癌治疗八年后被诊断出患有心房黏液瘤。该患者于2012年接受了化疗放疗(纵隔区域),以治疗III - A期肺腺癌。在2020年的随访成像中,检测到一个具有心脏黏液瘤特征的左心房肿块。回顾2017年在先前接受过放疗的纵隔区域的计算机断层扫描(CT),心脏肿块被追溯识别出来。对心脏肿块进行了手术切除,随后的病理检查证实了黏液瘤的诊断。据我们所知,这是首例报道的在先前接受过肺腺癌治疗的患者中出现左心房黏液瘤的病例,也是首例在先前接受过放疗的部位发生心房黏液瘤的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/d3d80b3d928d/life-13-01585-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/65082d71bafa/life-13-01585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/f837a7dc2013/life-13-01585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/4b72125103c4/life-13-01585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/fe608a13459a/life-13-01585-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/d3d80b3d928d/life-13-01585-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/65082d71bafa/life-13-01585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/f837a7dc2013/life-13-01585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/4b72125103c4/life-13-01585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/fe608a13459a/life-13-01585-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10381263/d3d80b3d928d/life-13-01585-g005.jpg

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Int J Mol Sci. 2023 Mar 21;24(6):5938. doi: 10.3390/ijms24065938.
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Crizotinib in MET Exon 14-Mutated or MET-Amplified in Advanced Disease Non-Small Cell Lung Cancer: A Retrospective, Single Institution Experience.
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克唑替尼治疗 MET 外显子 14 突变或 MET 扩增的晚期非小细胞肺癌:一项回顾性、单机构经验。
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Cardiac myxomas: A narrative review.心脏黏液瘤:一篇叙述性综述。
World J Cardiol. 2022 Apr 26;14(4):206-219. doi: 10.4330/wjc.v14.i4.206.
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