Witte S, Langer J, Stolte M
Z Gastroenterol. 1986 Jul;24(7):353-6.
1977 cases with gastric complains but without localized findings like ulcer or cancer were investigated by gastroscopy with biopsies of corpus and antrum ventriculi. We found in 5.5% an isolated mucosal atrophy of the gastric corpus (mean age 67.2 years compared to 59.4 years in cases with normal mucosa). 0.7% showed an atrophic gastritis of the antral mucosa, 0.9% an atrophic gastritis of the body and the antrum. Most of the cases with an isolated atrophy of the gastric body gave findings of hematologic disturbances. In all cases with isolated atrophy of the gastric body, including localized findings in the stomach, we found in 10.8% neoplastic processes, in another 3.9% hyperplasiogenic polyps. It seems to us of clinical importance to evaluate the gastric histology of the antral and body mucosa routinely because of the high incidence of pernicious anemia-like gastric atrophy and its relation to gastric neoplasias.
对1977例有胃部不适但无溃疡或癌症等局部病变的患者进行了胃镜检查，并对胃体和胃窦进行活检。我们发现5.5%的患者存在孤立性胃体黏膜萎缩（平均年龄67.2岁，而黏膜正常的患者平均年龄为59.4岁）。0.7%的患者表现为胃窦黏膜萎缩性胃炎，0.9%的患者表现为胃体和胃窦萎缩性胃炎。大多数孤立性胃体萎缩的患者有血液学紊乱表现。在所有孤立性胃体萎缩的病例中，包括胃部有局部病变的病例，我们发现10.8%有肿瘤性病变，另有3.9%有增生性息肉。鉴于恶性贫血样胃萎缩的高发病率及其与胃肿瘤的关系，我们认为常规评估胃窦和胃体黏膜的组织学具有临床重要性。
