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碳酸钾促进的α,β-不饱和羰基化合物与萘酚的氧-迈克尔加成/环化反应：萘并吡喃的合成

KCO-Promoted oxy-Michael Addition/Cyclization of ,-Unsaturated Carbonyl Compounds with Naphthols: Synthesis of Naphthopyrans.

作者信息

Li Shan-Shan, Zhao Li-Li, Pan Min, Feng Na, Peng Jin-Bao, Ma Ai-Jun

机构信息

School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.

出版信息

Molecules. 2023 Jul 19;28(14):5502. doi: 10.3390/molecules28145502.

DOI:10.3390/molecules28145502
PMID:37513372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10385152/
Abstract

A potassium carbonate promoted tandem oxy-Michael addition/cyclization of ,-unsaturated carbonyl compounds with naphthol derivatives for the synthesis of 2-substituted naphthopyrans was developed. Using the readily available, inexpensive potassium carbonate as the promoter, a range of different substituted naphthopyrans were prepared.

摘要

开发了一种碳酸钾促进的α,β-不饱和羰基化合物与萘酚衍生物的串联氧-迈克尔加成/环化反应，用于合成2-取代萘并吡喃。使用易于获得的廉价碳酸钾作为促进剂，制备了一系列不同取代的萘并吡喃。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/5619f1d62bc3/molecules-28-05502-sch006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/b02751c2dc5c/molecules-28-05502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/e35e70ca7748/molecules-28-05502-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/e5c0fa06e706/molecules-28-05502-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/6e03b80b00cb/molecules-28-05502-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/7109e590025c/molecules-28-05502-sch004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/b852f206c487/molecules-28-05502-sch005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/5619f1d62bc3/molecules-28-05502-sch006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/b02751c2dc5c/molecules-28-05502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/e35e70ca7748/molecules-28-05502-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/e5c0fa06e706/molecules-28-05502-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/6e03b80b00cb/molecules-28-05502-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/7109e590025c/molecules-28-05502-sch004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/b852f206c487/molecules-28-05502-sch005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ee/10385152/5619f1d62bc3/molecules-28-05502-sch006.jpg

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本文引用的文献

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Enantioselective Dehydrative γ-Arylation of α-Indolyl Propargylic Alcohols with Phenols: Access to Chiral Tetrasubstituted Allenes and Naphthopyrans.手性α-吲哚丙炔醇与酚的对映选择性脱水γ-芳基化反应：构建手性四取代烯丙基化合物和萘并吡喃。
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